Optical probe-based biosensors (OPBs) have proven instrumental in human health
monitoring. The growing portability and miniaturization of OPBs have rendered them cost …

Phosphoryl guanidine oligonucleotides (PGOs) are promising tools for biological research
and development of biosensors and therapeutics. We performed structural and hybridization …

In this work, we present new oligonucleotide derivatives containing inter-nucleotide N-
benzimidazole, N-benzoxazole, N-benzothiazole, and 1, 3-dimethyl-N-benzimidazole …

In this work, we for the first time conducted a detailed study on the structure, dynamics, and
hybridization properties of N-benzimidazole group–bearing phosphoramide benzoazole …

The development of new convenient tools for the design of multicomponent nucleic acid
(NA) complexes is one of the challenges in biomedicine and NA nanotechnology. In this …

8-oxoguanine (oxoG) is formed in DNA by the action of reactive oxygen species. As a highly
mutagenic and the most common oxidative DNA lesion, it is an important marker of oxidative …

Fluorophore (FD) labeling is widely used for detection and quantification of various
compounds bound to nanocarriers. The systems, composed of gold nanoparticles (GNPs) …

Imetelstat (GRN163L) is a potent and specific telomerase inhibitor currently in clinical
development for the treatment of hematological malignancies such as myelofibrosis and …

Methylenecarboxamide (glycine) morpholine oligomers (gMOs) with a modified backbone
are new and promising nucleic acid analogues. In this work, a combination of circular …

Genome-editing systems, being some of the key tools of molecular biologists, represent a
reasonable hope for progress in the field of personalized medicine. A major problem with …