The byproducts of bacterial fermentation known as short-chain fatty acids (SCFAs) are
chemically comprised of a carboxylic acid component and a short hydrocarbon chain …

In addition to being a part of the metabolic fatty acid fuel cycle, butyrate is also capable of
inducing growth arrest in a variety of normal cell types and senescence-like phenotypes in …

Aims Butyric acid (BUT), a short chain fatty acid produced daily by the gut microbiota, has
proven beneficial in models of cardiovascular diseases. With advancements in cancer …

Rationale: Reperfusion injury accounts for up to half of myocardial infarct size, and
meaningful clinical therapies targeting it do not exist. We have reported previously that …

JPM | Free Full-Text | Short-Chain Fatty Acids in Gut–Heart Axis: Their Role in the
Pathology of Heart Failure Next Article in Journal Precision Medicine in Radiomics and …

The understanding of gut microbiota has emerged as a significant frontier in development of
strategies to maintain normal human body's homeostasis and preventing the disease …

Background: Evidence reveals that histone deacetylase (HDAC) inhibition has potential for
the treatment of inflammatory diseases. The protective effect of HDAC inhibition involves …

Coronary artery disease (CAD) is the leading cause of morbidity and mortality. CAD has
both genetic and environmental causes. In the past two decades, the understanding of …

ABSTRACT Preclinical Research Neuropsychiatric disorders are a heterogeneous group of
conditions that often share underlying mitochondrial dysfunction and biological pathways …

Microbial metabolites have emerged as key players in the interplay between diet, the gut
microbiome, and host health. Two major classes, short-chain fatty acids (SCFAs) and …