Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …

Inhibiting cell survival and inducing cell death are the main approaches of tumor therapy.
Autophagy plays an important role on intracellular metabolic homeostasis by eliminating …

Ethnopharmacological relevance Licorice is a medicinal herb with a 2000-year history of
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …

Ethnopharmacological relevance Licorice has been commonly used in traditional Chinese
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …

Simple Summary Isoliquiritigenin (ISL), a natural bioactive compound with a chalcone
structure, demonstrates high antitumor efficacy. This review presents a summary of the latest …

Background Pancreatic cancer has been characterized by poor prognosis, early metastasis
and dissatisfactory treatment outcome. The high basal level of autophagy in tumor cells …

Ovarian cancer is mostly diagnosed at an advanced stage due to the absence of effective
screening methods and specific symptoms. Repeated chemotherapy resistance and …

Bioactive plant derived compounds are important for a wide range of therapeutic
applications, and some display promising anticancer properties. Further evidence suggests …

Plants have always been an important source of medicines for humans, and licorice is a very
significant herb in the development of humans. As a traditional herb, it is widely cultivated in …