Abnormalities in sex hormones and sexual dysfunction in males with diabetes mellitus: A mechanistic insight

N Andlib, M Sajad, R Kumar, SC Thakur - Acta Histochemica, 2023 - Elsevier
Diabetes is a considerate metabolic disorder that can lead to a series of complications,
involving the malfunctioning of the reproductive system of males. It has been observed that …

Diabetes associated with male reproductive system damages: Onset of presentation, pathophysiological mechanisms and drug intervention

GJ Shi, ZM Li, J Zheng, J Chen, XX Han, J Wu… - Biomedicine & …, 2017 - Elsevier
Diabetes mellitus (DM) is a major health problem that affects patients' quality of life quality
throughout the world due to its many complications. Reproductive dysfunction is one of the …

Selenium nanoparticles attenuate oxidative stress and testicular damage in streptozotocin-induced diabetic rats

MA Dkhil, R Zrieq, S Al-Quraishy, AE Abdel Moneim - Molecules, 2016 - mdpi.com
We investigated the protective and antioxidative effects of selenium nanoparticles (SeNPs)
in streptozotocin STZ-induced diabetic rats. STZ-diabetic rats were exposed daily to …

Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/HO-1 signaling pathway

Y Guo, J Sun, T Li, Q Zhang, S Bu, Q Wang, D Lai - Scientific Reports, 2017 - nature.com
Decline in semen quality has become a global public health concern. Psychological stress is
common in the current modern society and is associated with semen decline. Increasing …

[HTML][HTML] Melatonin protects the heart and pancreas by improving glucose homeostasis, oxidative stress, inflammation and apoptosis in T2DM-induced rats

DA Abdulwahab, MA El-Missiry, S Shabana, AI Othman… - Heliyon, 2021 - cell.com
Cardiomyopathy and pancreatic injury are health issues associated with type 2 diabetes
mellitus (T2DM) and are characterized by elevated oxidative stress, inflammation and …

Protective effects of melatonin against oxidative stress induced by metabolic disorders in the male reproductive system: A systematic review and meta-analysis of …

N Dehdari Ebrahimi, A Sadeghi, M Ala… - Frontiers in …, 2023 - frontiersin.org
Background Male infertility is a multifaceted issue that has gained scientific interest due to its
increasing rate. Studies have demonstrated that oxidative stress is involved in male infertility …

Melatonin ameliorates myocardial infarction in obese diabetic individuals: the possible involvement of macrophage apoptotic factors

J Maity, T Dey, A Banerjee… - Journal of Pineal …, 2023 - Wiley Online Library
In recent days, the hike in obesity‐mediated epidemics across the globe and the prevalence
of obesity‐induced cardiovascular disease has become one of the chief grounds for …

Mitochondrial functions and melatonin: a tour of the reproductive cancers

LG de Almeida Chuffa, FRF Seiva, MS Cucielo… - Cellular and Molecular …, 2019 - Springer
Cancers of the reproductive organs have a strong association with mitochondrial defects,
and a deeper understanding of the role of this organelle in preneoplastic–neoplastic …

A systematic review on the role of melatonin and its mechanisms on diabetes-related reproductive impairment in non-clinical studies

M Armandeh, B Bameri, H Haghi-Aminjan… - Frontiers in …, 2022 - frontiersin.org
Background Diabetes-induced reproductive complications can lead to subfertility and
infertility, raising the need to protect reproductive organs. There are limited medications …

Melatonin attenuates radiofrequency radiation (900 MHz)-induced oxidative stress, DNA damage and cell cycle arrest in germ cells of male Swiss albino mice

N Pandey, S Giri - Toxicology and industrial health, 2018 - journals.sagepub.com
Increasing male infertility of unknown aetiology can be associated with environmental
factors. Extensive use of mobile phones has exposed the general population to …