Mechanisms, applications, and challenges of insect RNA interference

KY Zhu, SR Palli - Annual review of entomology, 2020 - annualreviews.org
The RNA interference (RNAi) triggered by short/small interfering RNA (siRNA) was
discovered in nematodes and found to function in most living organisms. RNAi has been …

Antimicrobial peptides as potential antiviral factors in insect antiviral immune response

M Feng, S Fei, J Xia, V Labropoulou… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) with antiviral activity (antiviral peptides: AVPs) have become
a research hotspot and already show immense potential to become pharmaceutically …

Improving RNAi efficiency for pest control in crop species

S Yan, B Ren, B Zeng, J Shen - BioTechniques, 2020 - Taylor & Francis
The application of RNAi promotes the development of novel approaches toward plant
protection in a sustainable way. Genetically modified crops expressing dsRNA have been …

A balance between vector survival and virus transmission is achieved through JAK/STAT signaling inhibition by a plant virus

YM Wang, YZ He, XT Ye, T Guo… - Proceedings of the …, 2022 - National Acad Sciences
Viruses pose a great threat to animal and plant health worldwide, with many being
dependent on insect vectors for transmission between hosts. While the virus–host arms race …

RNA interference in insects: the link between antiviral defense and pest control

J Niu, R Chen, JJ Wang - Insect science, 2024 - Wiley Online Library
RNA interference (RNAi) is a form of gene silencing triggered by double‐stranded RNA
(dsRNA) that operates in all eukaryotic cells. RNAi has been widely investigated in insects to …

Honey bee and bumble bee antiviral defense

AJ McMenamin, KF Daughenbaugh, F Parekh… - Viruses, 2018 - mdpi.com
Bees are important plant pollinators in both natural and agricultural ecosystems. Managed
and wild bees have experienced high average annual colony losses, population declines …

Topical dsRNA delivery induces gene silencing and mortality in the pea aphid

J Niu, WJ Yang, Y Tian, JY Fan, C Ye… - Pest Management …, 2019 - Wiley Online Library
BACKGROUND With the growing number of available aphid genomes and transcriptomes,
an efficient and easy‐to‐adapt tool for gene function study is urgently required. RNA …

Partitiviruses infecting Drosophila melanogaster and Aedes aegypti exhibit efficient biparental vertical transmission

ST Cross, BL Maertens, TJ Dunham… - Journal of …, 2020 - Am Soc Microbiol
Partitiviruses are segmented, multipartite double-stranded RNA (dsRNA) viruses that until
recently were only known to infect fungi, plants, and protozoans. Metagenomic surveys have …

Rethink RNAi in insect pest control: challenges and perspectives

J Niu, CNT Taning, O Christiaens, G Smagghe… - Advances in insect …, 2018 - Elsevier
RNA interference (RNAi), usually referring to the small interfering (si) RNA pathway, is
promising in the development of a new generation of insect pest control products. However …

Investigating the Evolution of Drosophila STING-Dependent Antiviral Innate Immunity by Multispecies Comparison of 2′3′-cGAMP Responses

L Hédelin, A Thiébaut, J Huang, X Li… - Molecular Biology …, 2024 - academic.oup.com
Viruses represent a major threat to all animals, which defend themselves through induction
of a large set of virus-stimulated genes that collectively control the infection. In vertebrates …