Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription
ME Wilkinson, CJ Frangieh, RK Macrae, F Zhang - Science, 2023 - science.org
Non–long terminal repeat (non-LTR) retrotransposons, or long interspersed nuclear
elements (LINEs), are an abundant class of eukaryotic transposons that insert into genomes …
elements (LINEs), are an abundant class of eukaryotic transposons that insert into genomes …
[HTML][HTML] Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase
SC Pimentel, HE Upton, K Collins - Journal of Biological Chemistry, 2022 - ASBMB
Broad evolutionary expansion of polymerase families has enabled specialization of their
activities for distinct cellular roles. In addition to template-complementary synthesis, many …
activities for distinct cellular roles. In addition to template-complementary synthesis, many …
Telomere‐Specialized Retroelements in Drosophila: Adaptive Symbionts of the Genome, Neutral, or in Conflict?
DN Markova, SM Christensen, E Betrán - Bioessays, 2020 - Wiley Online Library
Linear chromosomes shorten in every round of replication. In Drosophila, telomere‐
specialized long interspersed retrotransposable elements (LINEs) belonging to the jockey …
specialized long interspersed retrotransposable elements (LINEs) belonging to the jockey …
[HTML][HTML] Conserved and divergent DNA recognition specificities and functions of R2 retrotransposon N-terminal domains
RJ Lee, CA Horton, B Van Treeck, JJR McIntyre… - Cell Reports, 2024 - cell.com
R2 non-long terminal repeat (non-LTR) retrotransposons are among the most extensively
distributed mobile genetic elements in multicellular eukaryotes and show promise for …
distributed mobile genetic elements in multicellular eukaryotes and show promise for …
Distinct and overlapping RNA determinants for binding and target-primed reverse transcription by Bombyx mori R2 retrotransposon protein
A Rodríguez-Vargas, K Collins - Nucleic Acids Research, 2024 - academic.oup.com
Eukaryotic retrotransposons encode a reverse transcriptase that binds RNA to template DNA
synthesis. The ancestral non-long terminal repeat (non-LTR) retrotransposons encode a …
synthesis. The ancestral non-long terminal repeat (non-LTR) retrotransposons encode a …
Completion of LINE integration involves an open '4-way'branched DNA intermediate
BB Khadgi, A Govindaraju… - Nucleic Acids …, 2019 - academic.oup.com
Abstract Long Interspersed Elements (LINEs), also known as non-LTR retrotransposons,
encode a multifunctional protein that reverse transcribes its mRNA into DNA at the site of …
encode a multifunctional protein that reverse transcribes its mRNA into DNA at the site of …
The linker region of LINEs modulates DNA cleavage and DNA polymerization
M Pradhan, A Govindaraju, A Jagdish… - Analytical …, 2020 - Elsevier
Long interspersed elements (LINEs) replicate by target primed reverse transcription (TPRT).
Insertion involves two half reactions. Each half reaction involves DNA cleavage followed by …
Insertion involves two half reactions. Each half reaction involves DNA cleavage followed by …
Global Mapping of Protein-Nucleic Acid Interaction of the RLE Line R2Bm
S Dhamala - 2022 - search.proquest.com
Abstract The R2 Long Interspersed Nucleotide Elements (LINEs) is a widely distributed site
specific non-LTR retrotransposons that integrates exclusively into host genome's 28s rRNA …
specific non-LTR retrotransposons that integrates exclusively into host genome's 28s rRNA …