Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Anthracyclines are ranked among the most effective chemotherapeutics against cancer.
They are glycoside drugs comprising the amino sugar daunosamine linked to a hydroxy …

PURPOSE To provide evidence-based recommendations to practicing clinicians on the
management of patients with small-cell lung cancer. METHODS An Expert Panel of medical …

Abstract NAD (P) H: Quinone Oxidoreductase 1 (NQO1) is an antioxidant enzyme that
catalyzes the two-electron reduction of several different classes of quinone-like compounds …

Tumour suppressor genes play a cardinal role in the development of a large array of human
cancers, including lung cancer, which is one of the most frequently diagnosed cancers …

This study examined the activity and safety of amrubicin monotherapy among relapsed small-
cell lung cancer (SCLC) patients who had previously been treated with atezolizumab plus …

Natural products have multifarious bioactivities against bacteria, fungi, viruses, cancers and
other diseases due to their diverse structures. Nearly 65% of anticancer drugs are natural …

Abstract Treatment for small cell lung cancer (SCLC) has not changed significantly
compared to the overwhelming development of targeted therapies for non-small cell lung …

Introduction Traditionally, relapsed SCLC has been classified as “sensitive” or “refractory” on
the basis of cutoff values (60 or 90 d) for the duration between the last chemotherapy and …

Objective It remains unclear what the best second-line treatment is for patients with small-
cell lung cancer sensitive to previous platinum-based chemotherapy. Methods We …