Metformin as an emerging concern in wastewater: Occurrence, analysis and treatment methods
Metformin is a wonder drug used as an anti-hypoglycemic medication; it is also used as a
cancer suppression medicament. Metformin is a first line of drug choice used by doctors for …
cancer suppression medicament. Metformin is a first line of drug choice used by doctors for …
Chiral monolithic silica-based HPLC columns for enantiomeric separation and determination: functionalization of chiral selector and recognition of selector-selectand …
This review draws attention to the use of chiral monolithic silica HPLC columns for the
enantiomeric separation and determination of chiral compounds. Properties and advantages …
enantiomeric separation and determination of chiral compounds. Properties and advantages …
Experimental design methodology for optimization and robustness determination in ion pair RP-HPLC method development: Application for the simultaneous …
MA Mahrouse, NT Lamie - Microchemical Journal, 2019 - Elsevier
Experimental design methodology (DOE) surpasses traditional (one variable at a time)
approach in improving the chromatographic separation performance with minimum effort …
approach in improving the chromatographic separation performance with minimum effort …
A validated LC-MS/MS method for simultaneous determination of linagliptin and metformin in spiked human plasma coupled with solid phase extraction: application to …
BA Moussa, MA Mahrouse, MG Fawzy - Journal of pharmaceutical and …, 2019 - Elsevier
Combination therapy has a pivotal role in type II diabetes mellitus management in patients
unable to maintain normal glycemic level using metformin alone. Addition of linagliptin …
unable to maintain normal glycemic level using metformin alone. Addition of linagliptin …
Development and validation of rapid RP-HPLC and green second-derivative UV spectroscopic methods for simultaneous quantification of metformin and remogliflozin …
M Attimarad, REE Elgorashe, R Subramaniam… - Separations, 2020 - mdpi.com
Recently, a new formulation containing metformin HCl (MFH) and remogliflozin etabonate
(RGE) has been approved for the management of diabetes mellitus. However, only one …
(RGE) has been approved for the management of diabetes mellitus. However, only one …
Development and validation of green UV derivative spectrophotometric methods for simultaneous determination metformin and remogliflozin from formulation …
The recent trend in green analytical chemistry is the development of green analytical
methods using environmentally friendly solvents. Therefore, three ecofriendly manipulated …
methods using environmentally friendly solvents. Therefore, three ecofriendly manipulated …
Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
Metformin, an anti-diabetes drug, has been recently emerging as a potential “anti-aging”
intervention based on its reported beneficial actions against aging in preclinical studies …
intervention based on its reported beneficial actions against aging in preclinical studies …
Application of experimental design in HPLC method optimization and robustness for the simultaneous determination of canagliflozin, empagliflozin, linagliptin, and …
BA Moussa, MA Mahrouse… - Biomedical …, 2021 - Wiley Online Library
Gliflozins and gliptins represent two different pharmacological drug classes that exert
different and potentially complementary glucose‐lowering effect in patients with type II …
different and potentially complementary glucose‐lowering effect in patients with type II …
A new strategy for the determination of the antidiabetics alogliptin, saxagliptin and vildagliptin using all-solid state potentiometric sensors
AR Derar, N Ahmed, EM Hussien - BMC chemistry, 2023 - Springer
Herein, we report on the development of disposable screen printed carbon, nanostructure
thin film Au/Pt and Pt/Pt all-solid state potentiometric sensors for some antidiabetic …
thin film Au/Pt and Pt/Pt all-solid state potentiometric sensors for some antidiabetic …
Mixed-mode solid phase extraction combined with LC-MS/MS for determination of empagliflozin and linagliptin in human plasma
PA Shah, PS Shrivastav, A George - Microchemical Journal, 2019 - Elsevier
A selective, sensitive, precise and accurate liquid chromatography-tandem mass
spectrometry method was developed and validated for the concurrent determination of …
spectrometry method was developed and validated for the concurrent determination of …