[HTML][HTML] Design, synthesis, and docking studies of novel pyrazole-based scaffolds and their evaluation as VEGFR2 inhibitors in the treatment of prostate cancer
DH Soliman, MS Nafie - RSC advances, 2023 - pubs.rsc.org
Since VEGFR-2 plays a crucial role in tumor growth, angiogenesis, and metastasis, it is a
prospective target for cancer treatment. In this work, a series of 3-phenyl-4-(2-substituted …
prospective target for cancer treatment. In this work, a series of 3-phenyl-4-(2-substituted …
[HTML][HTML] Five and six membered heterocyclic rings endowed with azobenzene as dual EGFR T790M and VEGFR-2 inhibitors: design, synthesis, in silico ADMET …
KE Anwer, SSA El-Hddad, NEA Abd El-Sattar… - RSC …, 2023 - pubs.rsc.org
Novel azobenzene scaffold-joined heterocyclic isoxazole, pyrazole, triazole, and/or triazine
moieties have been developed and synthesized utilizing microwave and traditional …
moieties have been developed and synthesized utilizing microwave and traditional …
Spectral characterization, DFT, docking and cytotoxicity of N-benzyl-4, 5-dihydro-3-methyl-5-oxo-1H-pyrazole-4-carbothioamide and its metal complexes
NM Hosny, A Belal, R Motawea, MA Hussien… - Journal of Molecular …, 2021 - Elsevier
A new ligand N-benzyl-4, 5-dihydro-3-methyl-5-oxo-1H-pyrazole-4-carbothioamide (H 2 L)
and some of its divalent metal complexes were synthesized. Elemental analyses, mass …
and some of its divalent metal complexes were synthesized. Elemental analyses, mass …
Diastereoselective synthesis of indolenine-based spiro [pyrazolone-4, 2′-pyrrolidine] scaffolds via 1, 3-dipolar cycloaddition of 4-aminopyrazolones, aldehydes, and …
S Nawaz, S Wei, Y Huang, W Wang, J Qu… - Organic & Biomolecular …, 2021 - pubs.rsc.org
In this work, we report a one-pot [3+ 2] cycloaddition of 4-aminopyrazolones, indolenines,
and aldehydes. The reaction utilized in situ generated azomethine ylides as 1, 3-dipoles and …
and aldehydes. The reaction utilized in situ generated azomethine ylides as 1, 3-dipoles and …
[PDF][PDF] RUSNAC ROMAN
Ş DOCTORALĂ, Ș BIOLOGICE, C GEONOMICE… - 2021 - cnaa.md
Rusnac Roman:" Design and synthesis of biologically active compounds of 3d metals with N
(4)-substituted thiosemicarbazones of 2-formylpyridine derivatives", PhD thesis in chemical …
(4)-substituted thiosemicarbazones of 2-formylpyridine derivatives", PhD thesis in chemical …