Optimal management of neutropenic fever in patients with cancer

AJ Zimmer, AG Freifeld - Journal of oncology practice, 2019 - ascopubs.org
Febrile neutropenia remains an important complication of treatment with cytotoxic
chemotherapy. It is often the first and sometimes the only sign or symptom of infection in this …

Oncologic emergencies: recognition and initial management

ML Higdon, CJ Atkinson, KV Lawrence - American family physician, 2018 - aafp.org
Most oncologic emergencies can be classified as metabolic, hematologic, structural, or
treatment related. Tumor lysis syndrome is a metabolic emergency that presents as severe …

Outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America …

RA Taplitz, EB Kennedy, EJ Bow, J Crews… - Journal of Clinical …, 2018 - ascopubs.org
Purpose To provide an updated joint ASCO/Infectious Diseases Society of American (IDSA)
guideline on outpatient management of fever and neutropenia in patients with cancer …

Inappropriate empirical antibiotic treatment in high-risk neutropenic patients with bacteremia in the era of multidrug resistance

G Martinez-Nadal, P Puerta-Alcalde… - Clinical Infectious …, 2020 - academic.oup.com
Background We aimed to describe the current rates of inappropriate empirical antibiotic
treatment (IEAT) in oncohematological patients with febrile neutropenia (FN) and its impact …

Impact of empirical antibiotic regimens on mortality in neutropenic patients with bloodstream infection presenting with septic shock

M Chumbita, P Puerta-Alcalde, C Gudiol… - Antimicrobial agents …, 2022 - Am Soc Microbiol
We analyzed risk factors for mortality in febrile neutropenic patients with bloodstream
infections (BSI) presenting with septic shock and assessed the impact of empirical antibiotic …

Bacterial pneumonia in patients with cancer: novel risk factors and management

JL Wong, SE Evans - Clinics in chest medicine, 2017 - chestmed.theclinics.com
Bacterial pneumonias cause disproportionate morbidity and mortality in patients with cancer,
despite the current aggressive use of prophylactic antibiotics and environmental hygiene …

Safety and efficacy of antibiotic de-escalation and discontinuation in high-risk hematological patients with febrile neutropenia: a single-center experience

A Verlinden, H Jansens, H Goossens… - Open forum …, 2022 - academic.oup.com
Background There is currently no consensus on optimal duration of antibiotic treatment in
febrile neutropenia. We report on the clinical impact of implementation of antibiotic de …

Clinical metagenomic sequencing of plasma microbial cell-free DNA for febrile neutropenia in patients with acute leukaemia

S Feng, G Rao, X Wei, R Fu, M Hou, Y Song… - Clinical Microbiology …, 2024 - Elsevier
Objectives To evaluate the diagnostic performance and clinical impact of metagenomic next-
generation sequencing (mNGS) of plasma microbial cell-free DNA (mcfDNA) in febrile …

Pediatric patients who receive antibiotics for fever and neutropenia in less than 60 min have decreased intensive care needs

JL Salstrom, RL Coughlin, K Pool… - Pediatric blood & …, 2015 - Wiley Online Library
Background Antibiotic delivery to patients with fever and neutropenia (F&N) in< 60 min is an
increasingly important quality measure for oncology centers, but several published reports …

Current antimicrobial practice in febrile neutropenia across Europe and Asia: the EBMT Infectious Disease Working Party survey

A Verlinden, M Mikulska, NS Knelange… - Bone marrow …, 2020 - nature.com
The aim of this survey was to summarize the current antimicrobial practice in febrile
neutropenia and the presence of key aspects of antimicrobial stewardship. A questionnaire …