Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis

WL Smith, Y Urade, PJ Jakobsson - Chemical reviews, 2011 - ACS Publications
Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …

Polyunsaturated fatty acids in male and female reproduction

DC Wathes, DRE Abayasekara… - Biology of …, 2007 - academic.oup.com
In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs)
far exceeds nutritional requirements. The ratio of n-6 to n-3 PUFAs is generally> 10: 1 …

Protein phosphorylation in mammalian spermatozoa

F Urner, D Sakkas - Reproduction, 2003 - rep.bioscientifica.com
Lipopolysaccharide (LPS), the endotoxin of Gram-negative bacteria, has detrimental effects
on the structure and function of bovine corpus luteum (CL) in vivo. The objective was to …

Cyclooxygenases, prostanoids, and tumor progression

MT Wang, KV Honn, D Nie - Cancer and Metastasis Reviews, 2007 - Springer
In response to various growth factors, hormones or cytokines, arachidonic acid can be
mobilized from phospholipids pools and converted to bioactive eicosanoids through …

Bacterial Lipopolysaccharide Induces an Endocrine Switch from Prostaglandin F to Prostaglandin E2 in Bovine Endometrium

S Herath, ST Lilly, DP Fischer, EJ Williams… - …, 2009 - academic.oup.com
Escherichia coli infection of the endometrium causes uterine disease after parturition and is
associated with prolonged luteal phases of the ovarian cycle in cattle. Termination of the …

Large-scale transcriptional analysis of bovine embryo biopsies in relation to pregnancy success after transfer to recipients

A El-Sayed, M Hoelker, F Rings… - Physiological …, 2006 - journals.physiology.org
The purpose of this work is to address the relationship between transcriptional profile of
embryos and the pregnancy success based on gene expression analysis of blastocyst …

Prostaglandin biosynthesis, transport, and signaling in corpus luteum: a basis for autoregulation of luteal function

JA Arosh, SK Banu, P Chapdelaine, E Madore… - …, 2004 - academic.oup.com
The corpus luteum (CL) is a transient ovarian endocrine gland formed from the ovulated
follicle. Progesterone is the primary secretory product of CL and is essential for …

Prostaglandin synthases: recent developments and a novel hypothesis

RJA Helliwell, LF Adams, MD Mitchell - Prostaglandins, Leukotrienes and …, 2004 - Elsevier
Cells are continuously exposed to cues, which signal cell survival or death. Fine-tuning of
these conflicting signals is essential for tissue development and homeostasis, and defective …

All in the family: aldose reductase and closely related aldo-keto reductases

JM Petrash - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
Aldose reductase catalyzes the first step in the polyol pathway and is thought to be involved
in the pathogenesis of diabetic complications. In addition to polyol synthesis, aldose …

Effect of interferon-τ on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of …

JA Arosh, SK Banu, S Kimmins, P Chapdelaine… - …, 2004 - academic.oup.com
Recognition and establishment of pregnancy involve several molecular and cellular
interactions among the conceptus, uterus, and corpus luteum (CL). In ruminants, interferon-τ …