Key Clinical Points Advanced Dementia Advanced dementia is a leading cause of death in
the United States. Features include profound memory deficits (eg, inability to recognize …

Elderly people confined to chronic care facilities face an increased risk of acquiring
infections by multidrug-resistant organisms (MDROs). This review presents the current …

Asymptomatic bacteriuria (ASB) is a common finding in many populations, including healthy
women and persons with underlying urologic abnormalities. The 2005 guideline from the …

Evidence-based guidelines for implementation and measurement of antibiotic stewardship
interventions in inpatient populations including long-term care were prepared by a …

Urinary tract infections (UTIs) are a significant cause of morbidity among older adults;
however, antibiotic prescriptions for clinically suspected UTIs are often inappropriate …

Importance Poor continuity of care may contribute to high health care spending and adverse
patient outcomes in dementia. Objective To examine the association between medical …

Importance Antibiotics are frequently and often inappropriately prescribed to patients in
nursing homes. These antibiotics pose direct risks to recipients and indirect risks to others …

1. Executive summary Multi-drug-resistant (MDR) Gram-negative bacterial infections have
become prevalent in some European countries. Moreover, increased use of broad-spectrum …

The topic of human longevity has invited extensive scientific and philosophic debate. Haller,
a prominent Swiss physiologist of the 18th century, thought that people ought to live to 200 …

Multimorbidity and polypharmacy are increasingly prevalent across healthcare systems and
settings as global demographic trends shift towards increased proportions of older people in …