New developments in the field of genomic technologies and their relevance to conservation management
Recent technological advances in the field of genomics offer conservation managers and
practitioners new tools to explore for conservation applications. Many of these tools are well …
practitioners new tools to explore for conservation applications. Many of these tools are well …
Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in Animals
Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …
maintenance. The farming practices have evolved mainly over the last century for …
Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice
C Kiourtis, A Wilczynska, C Nixon, W Clark… - Biology …, 2021 - journals.biologists.com
Mice are a widely used pre-clinical model system in large part due to their potential for
genetic manipulation. The ability to manipulate gene expression in specific cells under …
genetic manipulation. The ability to manipulate gene expression in specific cells under …
[HTML][HTML] Delivery strategies for CRISPR/Cas genome editing tool for retinal dystrophies: challenges and opportunities
CRISPR/Cas, an adaptive immune system in bacteria, has been adopted as an efficient and
precise tool for site-specific gene editing with potential therapeutic opportunities. It has been …
precise tool for site-specific gene editing with potential therapeutic opportunities. It has been …
Efficient CRISPR/Cas9-mediated genome modification of the glassy-winged sharpshooter Homalodisca vitripennis (Germar)
I de Souza Pacheco, ALA Doss, BG Vindiola… - Scientific reports, 2022 - nature.com
CRISPR/Cas9 technology enables the extension of genetic techniques into insect pests
previously refractory to genetic analysis. We report the establishment of genetic analysis in …
previously refractory to genetic analysis. We report the establishment of genetic analysis in …
Modifying mosquitoes to suppress disease transmission: Is the long wait over?
JR Powell - Genetics, 2022 - academic.oup.com
For more than 50 years it has been a dream of medical entomologists and public health
workers to control diseases like malaria and dengue fever by modifying, through genetics …
workers to control diseases like malaria and dengue fever by modifying, through genetics …
Genome editing in cotton: challenges and opportunities
Cotton has enormous economic potential providing high-quality protein, oil, and fibre. A
large increase in cotton output is necessary due to the world's changing climate and …
large increase in cotton output is necessary due to the world's changing climate and …
Genetic engineering and genome editing in plants, animals and humans: Facts and myths
M Platani, O Sokefun, E Bassil, Y Apidianakis - Gene, 2023 - Elsevier
Human history is inextricably linked to the introduction of desirable heritable traits in plants
and animals. Selective breeding (SB) predates our historical period and has been practiced …
and animals. Selective breeding (SB) predates our historical period and has been practiced …
Driving down malaria transmission with engineered gene drives
The last century has witnessed the introduction, establishment and expansion of mosquito-
borne diseases into diverse new geographic ranges. Malaria is transmitted by female …
borne diseases into diverse new geographic ranges. Malaria is transmitted by female …
Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations
AM Langmüller, J Champer, S Lapinska, L Xie… - Elife, 2022 - elifesciences.org
Abstract Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9
provides a highly efficient and flexible genome editing technology with numerous potential …
provides a highly efficient and flexible genome editing technology with numerous potential …