New developments in the field of genomic technologies and their relevance to conservation management

G Segelbacher, M Bosse, P Burger, P Galbusera… - Conservation …, 2022 - Springer
Recent technological advances in the field of genomics offer conservation managers and
practitioners new tools to explore for conservation applications. Many of these tools are well …

Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in Animals

AK Wani, N Akhtar, R Singh, A Prakash… - Veterinary research …, 2023 - Springer
Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …

Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice

C Kiourtis, A Wilczynska, C Nixon, W Clark… - Biology …, 2021 - journals.biologists.com
Mice are a widely used pre-clinical model system in large part due to their potential for
genetic manipulation. The ability to manipulate gene expression in specific cells under …

[HTML][HTML] Delivery strategies for CRISPR/Cas genome editing tool for retinal dystrophies: challenges and opportunities

A Lohia, DK Sahel, M Salman, V Singh… - Asian journal of …, 2022 - Elsevier
CRISPR/Cas, an adaptive immune system in bacteria, has been adopted as an efficient and
precise tool for site-specific gene editing with potential therapeutic opportunities. It has been …

Efficient CRISPR/Cas9-mediated genome modification of the glassy-winged sharpshooter Homalodisca vitripennis (Germar)

I de Souza Pacheco, ALA Doss, BG Vindiola… - Scientific reports, 2022 - nature.com
CRISPR/Cas9 technology enables the extension of genetic techniques into insect pests
previously refractory to genetic analysis. We report the establishment of genetic analysis in …

Modifying mosquitoes to suppress disease transmission: Is the long wait over?

JR Powell - Genetics, 2022 - academic.oup.com
For more than 50 years it has been a dream of medical entomologists and public health
workers to control diseases like malaria and dengue fever by modifying, through genetics …

Genome editing in cotton: challenges and opportunities

Z Khan, SH Khan, A Ahmed, MU Iqbal… - Journal of Cotton …, 2023 - Springer
Cotton has enormous economic potential providing high-quality protein, oil, and fibre. A
large increase in cotton output is necessary due to the world's changing climate and …

Genetic engineering and genome editing in plants, animals and humans: Facts and myths

M Platani, O Sokefun, E Bassil, Y Apidianakis - Gene, 2023 - Elsevier
Human history is inextricably linked to the introduction of desirable heritable traits in plants
and animals. Selective breeding (SB) predates our historical period and has been practiced …

Driving down malaria transmission with engineered gene drives

WT Garrood, P Cuber, K Willis, F Bernardini… - Frontiers in …, 2022 - frontiersin.org
The last century has witnessed the introduction, establishment and expansion of mosquito-
borne diseases into diverse new geographic ranges. Malaria is transmitted by female …

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

AM Langmüller, J Champer, S Lapinska, L Xie… - Elife, 2022 - elifesciences.org
Abstract Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9
provides a highly efficient and flexible genome editing technology with numerous potential …