Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

Aldosterone-producing adenomas (APAs) are the commonest curable cause of
hypertension. Most have gain-of-function somatic mutations of ion channels or transporters …

Alongside the lack of homogeneity among international guidelines and consensus
documents on primary hyperaldosteronism, the National UK guidelines on hypertension do …

Context Primary aldosteronism (PA) is one of the most common causes of secondary
hypertension, but the comparative outcomes of targeted treatment remain unclear …

Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of
hypertension. It is associated with a higher risk of cardiovascular, metabolic and renal …

This study assessed the clinical performance of point-of-care testing (POCT) for quick
cortisol assay (QCA) during adrenal vein sampling (AVS) using a newly invented portable …

The enzyme aldosterone synthase (CYP11B2) is specifically expressed in aldosterone-
producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing …

With the increasing volume of diagnostic imaging undertaken in an ageing population,
adrenal incidentalomas (AIs) are increasingly commonly seen. These masses are most …

Abstract Primary aldosteronism (PA) causes 5–10% of hypertension cases, but only a
minority of patients are currently diagnosed and treated because of a complex, stepwise …