Redox biology of respiratory viral infections

OA Khomich, SN Kochetkov, B Bartosch, AV Ivanov - Viruses, 2018 - mdpi.com
Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …

Role of Nrf2 and its activators in respiratory diseases

Q Liu, Y Gao, X Ci - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

The role of oxidative stress in the pathogenesis of infections with coronaviruses

C Gain, S Song, T Angtuaco, S Satta… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

[HTML][HTML] Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies

C Yao, S Dai, C Wang, K Fu, R Wu, X Zhao… - Biomedicine & …, 2023 - Elsevier
Luteolin is a flavonoid widely present in various traditional Chinese medicines. In recent
years, luteolin has received more attention due to its impressive liver protective effect, such …

[HTML][HTML] Neutrophils in respiratory viral infections

C Johansson, FCM Kirsebom - Mucosal immunology, 2021 - Elsevier
Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …

Implications of oxidative stress on viral pathogenesis

FC Camini, CC da Silva Caetano, LT Almeida… - Archives of …, 2017 - Springer
Reactive species are frequently formed after viral infections. Antioxidant defences, including
enzymatic and non-enzymatic components, protect against reactive species, but sometimes …

Redox-modulating agents in the treatment of viral infections

P Checconi, M De Angelis, ME Marcocci… - International Journal of …, 2020 - mdpi.com
Viruses use cell machinery to replicate their genome and produce viral proteins. For this
reason, several intracellular factors, including the redox state, might directly or indirectly …

Glutathione supplementation as an adjunctive therapy in COVID-19

V Guloyan, B Oganesian, N Baghdasaryan, C Yeh… - Antioxidants, 2020 - mdpi.com
Morbidity and mortality of coronavirus disease 2019 (COVID-19) are due in large part to
severe cytokine storm and hypercoagulable state brought on by dysregulated host …

Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK–NF-κB pathway

CH Yeh, JJ Yang, ML Yang, YC Li, YH Kuan - Free Radical Biology and …, 2014 - Elsevier
Acute lung injury (ALI) is a serious disease with unacceptably high mortality and morbidity
rates. Up to now, no effective therapeutic strategy for ALI has been established. Rutin …

Potential neurological effects of severe COVID-19 infection

D Nuzzo, P Picone - Neuroscience research, 2020 - Elsevier
Coronaviruses (CoVs) are large positive stranded enveloped RNA viruses that generally
cause enteric and respiratory diseases in humans and in animals. Most human CoVs have …