Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting
M Sadrkhanloo, M Entezari, S Orouei, A Zabolian… - Life Sciences, 2022 - Elsevier
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of redox balance
and it responds to various cell stresses that oxidative stress is the most well-known one. The …
and it responds to various cell stresses that oxidative stress is the most well-known one. The …
The Nrf2 pathway in ischemic stroke: a review
Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …
brain, is the leading cause of permanent disability and is among the leading causes of death …
Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO‐1 Pathway
Y Yang, B He, X Zhang, R Yang, X Xia… - Oxidative medicine …, 2022 - Wiley Online Library
Geraniin, a polyphenol isolated from Phyllanthus amarus, possesses extensive biological
and pharmaceutical activities. In this study, we investigated the protective effect against …
and pharmaceutical activities. In this study, we investigated the protective effect against …
Vitexin Improves Cerebral ischemia‑reperfusion Injury by Attenuating Oxidative Injury and Ferroptosis via Keap1/Nrf2/HO-1signaling
L Guo, L Shi - Neurochemical Research, 2023 - Springer
Cerebral ischemia/reperfusion involves multiple pathological processes and ferroptosis
played a crucial role in the disease progression. Nevertheless, whether Vitexin could …
played a crucial role in the disease progression. Nevertheless, whether Vitexin could …
[HTML][HTML] Biliverdin modulates the Nrf2/A20/eEF1A2 axis to alleviate cerebral ischemia-reperfusion injury by inhibiting pyroptosis
W Bai, S Huo, G Zhou, J Li, Y Yang, J Shao - Biomedicine & …, 2023 - Elsevier
This study aimed to examine whether Biliverdin, which is a common metabolite of haem, can
alleviate cerebral ischemia reperfusion injury (CIRI) by inhibiting pyroptosis. Here, CIRI was …
alleviate cerebral ischemia reperfusion injury (CIRI) by inhibiting pyroptosis. Here, CIRI was …
Nrf2/HO-1 signaling stimulation through acetyl-11-keto-beta-boswellic acid (AKBA) provides neuroprotection in ethidium bromide-induced experimental model of …
Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …
PI3K/AKT/mTOR signalling inhibitor chrysophanol ameliorates neurobehavioural and neurochemical defects in propionic acid-induced experimental model of autism …
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder marked by
social and communication deficits as well as repetitive behaviour. Several studies have …
social and communication deficits as well as repetitive behaviour. Several studies have …
Widely targeted metabolomics analysis of enriched secondary metabolites and determination of their corresponding antioxidant activities in Elaeagnus angustifolia var …
Y Wang, H Li, X Li, C Wang, Q Li, M Xu, X Guan, Z Lan… - Food Chemistry, 2022 - Elsevier
Elaeagnus angustifolia var. orientalis (L.) Kuntze fruit contains a large number of naturally
occurring molecules present as glycoside, methylated, and methyl ester conjugates, which …
occurring molecules present as glycoside, methylated, and methyl ester conjugates, which …
Role of plant-derived compounds in the molecular pathways related to inflammation
AJ Olędzka, ME Czerwińska - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammation is the primary response to infection and injury. Its beneficial effect is an
immediate resolution of the pathophysiological event. However, sustained production of …
immediate resolution of the pathophysiological event. However, sustained production of …