Production and use of antigen tetramers to study antigen-specific B cells
B cells generate antibodies that provide protection from infection, but also cause pathology
in autoimmune and allergic conditions. Antigen-specific B cells can be detected by binding …
in autoimmune and allergic conditions. Antigen-specific B cells can be detected by binding …
The α-Gal epitope-the cause of a global allergic disease
M Perusko, J Grundström, M Eldh, C Hamsten… - Frontiers in …, 2024 - frontiersin.org
The galactose-α-1, 3-galactose (α-Gal) epitope is the cause of a global allergic disease, the
α-Gal syndrome (AGS). It is a severe form of allergy to food and products of mammalian …
α-Gal syndrome (AGS). It is a severe form of allergy to food and products of mammalian …
Atypical and non-classical CD45RBlo memory B cells are the majority of circulating SARS-CoV-2 specific B cells following mRNA vaccination or COVID-19
Resting memory B cells can be divided into classical or atypical groups, but the
heterogenous marker expression on activated memory B cells makes similar classification …
heterogenous marker expression on activated memory B cells makes similar classification …
The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity
SG Tangye, J Mackie, K Pathmanandavel… - Immunological …, 2024 - Wiley Online Library
The essential role of B cells is to produce protective immunoglobulins (Ig) that recognize,
neutralize, and clear invading pathogens. This results from the integration of signals …
neutralize, and clear invading pathogens. This results from the integration of signals …
Anti-allergen monoclonal antibodies for the treatment of allergies
Background To tackle the growing allergy epidemic, novel therapeutic approaches are
urgently needed. One promising avenue is the development of anti-allergen antibody …
urgently needed. One promising avenue is the development of anti-allergen antibody …
Reservoirs of allergic memory
Reservoirs of allergic memory | Nature Reviews Immunology Skip to main content Thank you
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Pathogenic IgE-fated B cell memory retains functional plasticity
Long-lived immunoglobulin (Ig) E responses against innocuous environmental and dietary
antigens (Ags) are maintained by an IgG1-dominant memory B cell (MBC) compartment …
antigens (Ags) are maintained by an IgG1-dominant memory B cell (MBC) compartment …
Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract
Allergen-specific IgE is a key mediator of allergic asthma. However, the tissue sites and cell
types that support IgE production at the mucosa remained undefined. Here, we reveal that …
types that support IgE production at the mucosa remained undefined. Here, we reveal that …
Memory B cells with extraordinary longevity upon smallpox vaccination: Implications for type 1 hypersensitivities.
JB van Dam, AM Ehlers - Allergy, 2023 - search.ebscohost.com
Abstract Keywords: allergy; IgE; hypersensitivity; longevity; memory B cells EN allergy IgE
hypersensitivity longevity memory B cells 2805 2807 3 10/04/23 20231001 NES 231001 …
hypersensitivity longevity memory B cells 2805 2807 3 10/04/23 20231001 NES 231001 …
Monoklonale Anti-Allergen-Antikörper für die Behandlung von Allergien
Zusammenfassung Hintergrund: Um der wachsenden Allergie-Epidemie gerecht zu werden,
werden dringend neue therapeutische Ansätze benötigt. Diesbezüglich ist die Entwicklung …
werden dringend neue therapeutische Ansätze benötigt. Diesbezüglich ist die Entwicklung …