In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …

The BH3-only Bim protein is a major determinant for initiating the intrinsic apoptotic pathway
under both physiological and pathophysiological conditions. Tight regulation of its …

BH3-only proteins constitute major proportion of pro-apoptotic members of B-cell lymphoma
2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development …

Glucocorticoids (GCs) are steroids with profound anti-inflammatory and immunomodulatory
activities. Synthetic GCs are widely used for managing chronic inflammatory and …

High-dose glucocorticoids (GCs) can be a useful treatment for aggressive forms of chronic
lymphocytic leukemia (CLL). However, their mechanism of action is not well understood, and …

Glucocorticoids (GC) are important in the regulation of selection and apoptosis of CD4+
CD8+ double-positive (DP) thymocytes. The pronounced GC-sensitivity of DP thymocytes …

MicroRNAs (miRNAs), a new class of noncoding RNAs, which can hybridize to target
messenger RNAs and regulate their expression posttranscriptionally, express differentially …

Objectives The aim of this study was to investigate the expression levels of miR‐19a in non‐
small cell lung cancer (NSCLC) tissue and serum, and to clarify the relationships of serum …

Despite improvements in the therapeutic approaches for hematological malignancies in the
last decades, refractory disease still occurs, and cancer drug resistance still remains a major …

Children and adults with the most aggressive form of brain cancer, malignant gliomas or
glioblastoma, often develop cerebral edema as a life-threatening complication. This …