A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
[HTML][HTML] Regulation of Bim in health and disease
The BH3-only Bim protein is a major determinant for initiating the intrinsic apoptotic pathway
under both physiological and pathophysiological conditions. Tight regulation of its …
under both physiological and pathophysiological conditions. Tight regulation of its …
BH3-only protein BIM: an emerging target in chemotherapy
BH3-only proteins constitute major proportion of pro-apoptotic members of B-cell lymphoma
2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development …
2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development …
The role of microRNAs in glucocorticoid action
SA Clayton, SW Jones, M Kurowska-Stolarska… - Journal of Biological …, 2018 - ASBMB
Glucocorticoids (GCs) are steroids with profound anti-inflammatory and immunomodulatory
activities. Synthetic GCs are widely used for managing chronic inflammatory and …
activities. Synthetic GCs are widely used for managing chronic inflammatory and …
PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia
S Tung, Y Shi, K Wong, F Zhu… - Blood, The Journal …, 2013 - ashpublications.org
High-dose glucocorticoids (GCs) can be a useful treatment for aggressive forms of chronic
lymphocytic leukemia (CLL). However, their mechanism of action is not well understood, and …
lymphocytic leukemia (CLL). However, their mechanism of action is not well understood, and …
The regulation of the mitochondrial apoptotic pathway by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cells
L Prenek, F Boldizsár, R Kugyelka, E Ugor, G Berta… - Apoptosis, 2017 - Springer
Glucocorticoids (GC) are important in the regulation of selection and apoptosis of CD4+
CD8+ double-positive (DP) thymocytes. The pronounced GC-sensitivity of DP thymocytes …
CD8+ double-positive (DP) thymocytes. The pronounced GC-sensitivity of DP thymocytes …
The functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapy
C Luan, Z Yang, B Chen - OncoTargets and therapy, 2015 - Taylor & Francis
MicroRNAs (miRNAs), a new class of noncoding RNAs, which can hybridize to target
messenger RNAs and regulate their expression posttranscriptionally, express differentially …
messenger RNAs and regulate their expression posttranscriptionally, express differentially …
Serum miR‐19a expression correlates with worse prognosis of patients with non‐small cell lung cancer
Q Lin, T Chen, Q Lin, G Lin, J Lin… - Journal of surgical …, 2013 - Wiley Online Library
Objectives The aim of this study was to investigate the expression levels of miR‐19a in non‐
small cell lung cancer (NSCLC) tissue and serum, and to clarify the relationships of serum …
small cell lung cancer (NSCLC) tissue and serum, and to clarify the relationships of serum …
miRNAs mediated drug resistance in hematological malignancies
SP da Silva, HR Caires, R Bergantim… - Seminars in Cancer …, 2022 - Elsevier
Despite improvements in the therapeutic approaches for hematological malignancies in the
last decades, refractory disease still occurs, and cancer drug resistance still remains a major …
last decades, refractory disease still occurs, and cancer drug resistance still remains a major …
Dexamethasone alleviates tumor-associated brain damage and angiogenesis
Z Fan, T Sehm, M Rauh, M Buchfelder, IY Eyupoglu… - PloS one, 2014 - journals.plos.org
Children and adults with the most aggressive form of brain cancer, malignant gliomas or
glioblastoma, often develop cerebral edema as a life-threatening complication. This …
glioblastoma, often develop cerebral edema as a life-threatening complication. This …