[HTML][HTML] The relevance of oxidative stress in the pathogenesis and therapy of retinal dystrophies
E B. Domènech, G Marfany - Antioxidants, 2020 - mdpi.com
Retinal cell survival requires an equilibrium between oxygen, reactive oxygen species, and
antioxidant molecules that counteract oxidative stress damage. Oxidative stress alters cell …
antioxidant molecules that counteract oxidative stress damage. Oxidative stress alters cell …
[HTML][HTML] Reactive oxygen species-mediated damage of retinal neurons: Drug development targets for therapies of chronic neurodegeneration of the retina
LJ Rohowetz, JG Kraus, P Koulen - International Journal of Molecular …, 2018 - mdpi.com
The significance of oxidative stress in the development of chronic neurodegenerative
diseases of the retina has become increasingly apparent in recent years. Reactive oxygen …
diseases of the retina has become increasingly apparent in recent years. Reactive oxygen …
[HTML][HTML] Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK)
KT Chan, DA Bennin, A Huttenlocher - Journal of Biological Chemistry, 2010 - ASBMB
The coordinated and dynamic regulation of adhesions is required for cell migration. We
demonstrated previously that limited proteolysis of talin1 by the calcium-dependent protease …
demonstrated previously that limited proteolysis of talin1 by the calcium-dependent protease …
[HTML][HTML] Two combined photosensitizers: a goal for more effective photodynamic therapy of cancer
P Acedo, JC Stockert, M Cañete, A Villanueva - Cell death & disease, 2014 - nature.com
Photodynamic therapy (PDT) is a clinically approved therapeutic modality for the treatment
of diseases characterized by uncontrolled cell proliferation, mainly cancer. It involves the …
of diseases characterized by uncontrolled cell proliferation, mainly cancer. It involves the …
Zn-doped MnO2 nanocoating with enhanced catalase-mimetic activity and cytocompatibility protects pre-osteoblasts against H2O2-induced oxidative stress
S Liu, K Li, T Hu, D Shao, S Huang, Y Xie… - Colloids and Surfaces B …, 2021 - Elsevier
Therapeutic application in prevention and treatment of bone diseases, particularly
osteoporosis, has recently started to emerge for manganese dioxide (MnO 2) nanoparticles …
osteoporosis, has recently started to emerge for manganese dioxide (MnO 2) nanoparticles …
miR-193b–Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells
Well-differentiated and dedifferentiated liposarcomas (WDLS/DDLS) account for
approximately 13% of all soft tissue sarcoma in adults and cause substantial morbidity or …
approximately 13% of all soft tissue sarcoma in adults and cause substantial morbidity or …
The role of focal adhesion kinase in the regulation of cellular mechanical properties
CT Mierke - Physical biology, 2013 - iopscience.iop.org
The regulation of mechanical properties is necessary for cell invasion into connective tissue
or intra-and extravasation through the endothelium of blood or lymph vessels. Cell invasion …
or intra-and extravasation through the endothelium of blood or lymph vessels. Cell invasion …
Autism spectrum disorders may be due to cerebral toxoplasmosis associated with chronic neuroinflammation causing persistent hypercytokinemia that resulted in an …
J Prandota - Research in Autism Spectrum Disorders, 2010 - Elsevier
Worldwide, approximately 2 billion people are chronically infected with Toxoplasma gondii
with largely yet unknown consequences. Patients with autism spectrum disorders (ASD) …
with largely yet unknown consequences. Patients with autism spectrum disorders (ASD) …
[HTML][HTML] MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells
G Pratelli, D Carlisi, D Di Liberto, A Notaro… - International Journal of …, 2023 - mdpi.com
Triple-Negative Breast Cancer (TNBC) is a particularly aggressive subtype among breast
cancers (BCs), characterized by anoikis resistance, high invasiveness, and metastatic …
cancers (BCs), characterized by anoikis resistance, high invasiveness, and metastatic …
[HTML][HTML] Radiation sensitization of tumor cells induced by shear stress: The roles of integrins and FAK
Recent studies revealed that the interstitial fluid flow in and around tumor tissue not only
played an important role in delivering anticancer agents, but also affected the …
played an important role in delivering anticancer agents, but also affected the …