Endurance exercise is a widely accessible, low-cost intervention with a variety of benefits to
multiple organ systems. Exercise improves multiple indices of physical performance and …

Chronic diseases are major killers in the modern era. Physical inactivity is a primary cause
of most chronic diseases. The initial third of the article considers: activity and prevention …

Background Diet-induced obesity (DIO) is a significant health concern which has been
linked to structural and functional changes in the gut microbiota. Exercise (Ex) is effective in …

Abstract BACKGROUND. The American Cancer Society, the Centers for Disease Control
and Prevention (CDC), the National Cancer Institute (NCI), and the North American …

This year, more than 1 million Americans and more than 10 million people worldwide are
expected to be diagnosed with cancer, a disease commonly believed to be preventable …

Pathological and physiological stimuli, including acute exercise, activate autophagy;
however, it is unknown whether exercise training alters basal levels of autophagy and …

Colorectal cancer has been strongly associated with a Western lifestyle. In the past several
decades, much has been learned about the dietary, lifestyle, and medication risk factors for …

Insulin and insulin-like growth factor (IGF) axes are major determinants of proliferation and
apoptosis and thus may influence carcinogenesis. In various animal models, modulation of …

Diverticular disease is one of the most common conditions in the Western world and one of
the most common findings identified at colonoscopy. Recently, there has been a significant …

Collectively, cardiovascular disease (including stroke), cancer, and diabetes account for
approximately two thirds of all deaths in the United States and about $700 billion in direct …