Metabolomic and lipidomic biomarkers for premalignant liver disease diagnosis and therapy
In recent years, there has been a plethora of attempts to discover biomarkers that are more
reliable than α-fetoprotein for the early prediction and prognosis of hepatocellular carcinoma …
reliable than α-fetoprotein for the early prediction and prognosis of hepatocellular carcinoma …
Metabolomics in psychiatric disorders: What we learn from animal models
Biomarkers are a recent research target within biological factors of psychiatric disorders.
There is growing evidence for deriving biomarkers within psychiatric disorders in serum or …
There is growing evidence for deriving biomarkers within psychiatric disorders in serum or …
[HTML][HTML] Application of a hybrid zwitterionic hydrophilic interaction liquid chromatography column in metabolic profiling studies
Metabolic phenotyping studies using mouse liver extracts as a model, performed on a novel
zwitterionic HILIC UHPLC column, which is based on ethylene-bridged hybrid …
zwitterionic HILIC UHPLC column, which is based on ethylene-bridged hybrid …
Simultaneous determination of methylated nucleosides by HILIC–MS/MS revealed their alterations in urine from breast cancer patients
Z Fang, Y Hu, X Hong, X Zhang, T Pan, C Pan, S Zheng… - Metabolites, 2022 - mdpi.com
RNA methylation plays a vital role in the pathogenesis of a variety of diseases including
cancer, and aberrant levels of modified nucleosides in RNA were revealed to be related to …
cancer, and aberrant levels of modified nucleosides in RNA were revealed to be related to …
Rapid Characterizaiton of Chemical Constituents of the Tubers of Gymnadenia conopsea by UPLC–Orbitrap–MS/MS Analysis
X Wang, XJ Zhong, N Zhou, N Cai, JH Xu, QB Wang… - Molecules, 2020 - mdpi.com
Gymnadenia conopsea R. Br. is a traditional Tibetan medicinal plant that grows at altitudes
above 3000 m, which is used to treat neurasthenia, asthma, coughs, and chronic hepatitis …
above 3000 m, which is used to treat neurasthenia, asthma, coughs, and chronic hepatitis …
State-of-the-art in LC–MS Approaches for Probing the Polar Metabolome
Metabolomics is a rapidly growing research area that focuses on the systematic study of
small molecule metabolites found in various types of biological samples, such as tissues …
small molecule metabolites found in various types of biological samples, such as tissues …
Liver metabolomics identifies bile acid profile changes at early stages of alcoholic liver disease in mice
G Charkoftaki, WY Tan, P Berrios-Carcamo, DJ Orlicky… - 2022 - Elsevier
Alcohol consumption is a global healthcare problem with enormous social, economic, and
clinical consequences. The liver sustains the earliest and the greatest degree of tissue injury …
clinical consequences. The liver sustains the earliest and the greatest degree of tissue injury …
Metabolic phenotyping study of mouse brains following acute or chronic exposures to ethanol
O Deda, C Virgiliou, EG Armitage… - Journal of proteome …, 2020 - ACS Publications
The chronic and acute effect of ethanol administration on the metabolic phenotype of mouse
brain was studied in a C57BL/6 mouse model of ethanol abuse using both untargeted and …
brain was studied in a C57BL/6 mouse model of ethanol abuse using both untargeted and …
Evaluation of Cocaine Effect on Endogenous Metabolites of HepG2 Cells Using Targeted Metabolomics
Cocaine toxicity has been a subject of study because cocaine is one of the most common
and potent drugs of abuse. In the current study the effect of cocaine on human liver cancer …
and potent drugs of abuse. In the current study the effect of cocaine on human liver cancer …
Resolving metabolic heterogeneity in experimental models of the tumor microenvironment from a stable isotope resolved metabolomics perspective
TWM Fan, RM Higashi, Y Chernayavskaya, AN Lane - Metabolites, 2020 - mdpi.com
The tumor microenvironment (TME) comprises complex interactions of multiple cell types
that determines cell behavior and metabolism such as nutrient competition and immune …
that determines cell behavior and metabolism such as nutrient competition and immune …