Neoplastic ICAM-1 protects lung carcinoma from apoptosis through ligation of fibrinogen

SH Wang, JL Wang, C Liu, L Yang, XQ Tan… - Cell Death & …, 2024 - nature.com
Intercellular cell adhesion molecule-1 (ICAM-1) is frequently overexpressed in non-small
cell lung cancer (NSCLC) and associated with poor prognosis. However, the mechanism …

Computational investigations on reaction mechanisms of the covalent inhibitors ponatinib and analogs targeting the extracellular signal-regulated kinases

Y Tian, M Zhang, P Heng, H Hou, B Wang - International Journal of …, 2023 - mdpi.com
As an important cancer therapeutic target, extracellular signal-regulated kinases (ERK) are
involved in triggering various cellular responses in tumors. Regulation of the ERK signaling …

[HTML][HTML] Network pharmacology and molecular docking analysis on the mechanism of Wensan tincture in the treatment of pulmonary nodules: A review

J Zhang, J Yang, G Li - Medicine, 2024 - journals.lww.com
Network pharmacology and molecular docking methods were applied to elucidate the
molecular mechanism of action of Wensan tincture (WST) in the treatment of pulmonary …