YAP/TAZ is a master regulator of mechanotransduction whose functions rely on
translocation from the cytoplasm to the nucleus in response to diverse physical cues …

Simple Summary Neurons are biological wires that send signals not only across the brain,
but throughout the body. Like almost all cells in the human body, neurons adhere to their …

Cells are continuously exposed to physical forces and the central nervous system (CNS) is
no exception. Cells dynamically adapt their behavior and remodel the surrounding …

The serine/threonine kinase Cdk5 plays an essential role in neuronal positioning during
corticogenesis, but the underlying mechanisms are unknown. In nonneuronal cells, the …

Targeted deletion of focal adhesion kinase (fak) in the developing dorsal forebrain resulted
in local disruptions of the cortical basement membrane located between the …

Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain and are
highly enriched in polymerized F-actin, which drives the formation and maintenance of …

The formation of neuronal networks in the central nervous system (CNS) requires precise
control of axonal branch development and stabilization. Here we show that cell-specific …

Mechanical cues arising from extracellular matrices greatly affect cellular properties, and
hence, are of significance in designing biomaterials. In this study, a DNA crosslinked …

Axonal receptors for class 3 semaphorins (Sema3s) are heterocomplexes of neuropilins
(Nrps) and Plexin‐As signalling coreceptors. In the developing cerebral cortex, the Ig …

Cells form stress granules (SGs) in response to environmental stresses, which constitute
cytoplasmic domains where mRNAs are stored and translation is halted. Although several …