Patients suffering from iron overload can experience serious complications. In such patients,
various organs, such as endocrine glands and liver, can be damaged. Although iron is a …

Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in
the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from …

BACKGROUND AND OBJECTIVES: Iron accumulation is an inevitable consequence of
chronic blood transfusions and results in serious complications in the absence of chelation …

Recently introduced chelation regimens that combine deferoxamine (DFO) and deferiprone
have been shown to have greater efficacy in promoting iron excretion than either chelator …

Background To assess the literature for the impact of iron overload and infusion Iron
Chelation Therapy (ICT) on patients' quality of life (QoL), and the availability of QoL …

Multiple sclerosis (MS) is a chronic, immune-mediated, demyelinating disease of the central
nervous system of as yet unknown aetiology. A consensus of opinion has suggested that the …

Patients with thalassemia major accumulate body iron over time as a consequence of
continuous red blood cell transfusions which cause hepatic, endocrine, and cardiac …

Thalassemia major is an inherited hemoglobin disorder resulting in a chronic hemolytic
anemia. Transfusion therapy together with elevated gastrointestinal absorption of iron …

The simultaneous use of deferioxamine (DFO) and deferiprone (DFP) has an additive effect
in iron excretion in transfusion-dependent thalassemic patients. In a prospective study, we …

Background Iron overload, resulting from blood transfusions in patients with chronic
anemias, has historically been controlled with regular deferoxamine, but its parenteral …