The physics of heart rhythm disorders
WJ Rappel - Physics reports, 2022 - Elsevier
The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …
representing the most common cause of death around the world. There remains a need to …
The management of ventricular dysrhythmia in aconite poisoning
JM Coulson, TM Caparrotta, JP Thompson - Clinical Toxicology, 2017 - Taylor & Francis
Introduction: Aconite poisoning is relatively rare but is frequently complicated by ventricular
dysrhythmias, which may be fatal. Molecular basis of aconite alkaloid ventricular …
dysrhythmias, which may be fatal. Molecular basis of aconite alkaloid ventricular …
Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes
BO Bingen, MC Engels, MJ Schalij… - Cardiovascular …, 2014 - academic.oup.com
Aims Atrial fibrillation (AF) is the most common cardiac arrhythmia and often involves
reentrant electrical activation (eg spiral waves). Drug therapy for AF can have serious side …
reentrant electrical activation (eg spiral waves). Drug therapy for AF can have serious side …
Imaging the dynamics of individual electropores
JT Sengel, MI Wallace - Proceedings of the National …, 2016 - National Acad Sciences
Electroporation is a widely used technique to permeabilize cell membranes. Despite its
prevalence, our understanding of the mechanism of voltage-mediated pore formation is …
prevalence, our understanding of the mechanism of voltage-mediated pore formation is …
Drift and termination of spiral waves in optogenetically modified cardiac tissue at sub-threshold illumination
S Hussaini, V Venkatesan, V Biasci… - Elife, 2021 - elifesciences.org
The development of new approaches to control cardiac arrhythmias requires a deep
understanding of spiral wave dynamics. Optogenetics offers new possibilities for this …
understanding of spiral wave dynamics. Optogenetics offers new possibilities for this …
Nondestructive Electrical Activation Enables Multiple Life Cycles for Degraded Batteries
Appropriate treatment of mass‐produced degraded batteries is desired to alleviate resource
waste and environmental pollution caused by direct disposal. However, current …
waste and environmental pollution caused by direct disposal. However, current …
[PDF][PDF] Electroporation-induced changes in normal immature rat myoblasts (H9C2)
I Kaminska, M Kotulska, A Stecka, J Saczko… - Gen Physiol …, 2012 - academia.edu
Application of a high electric field causes an electric shock to the heart. This is utilized in defibrillationtoreestablishnormalcontraction…
arrest. If shock-induced transmembrane potentials are large enough, they can cause tissue …
arrest. If shock-induced transmembrane potentials are large enough, they can cause tissue …
Terminating spiral waves with a single designed stimulus: Teleportation as the mechanism for defibrillation
N DeTal, A Kaboudian… - Proceedings of the …, 2022 - National Acad Sciences
We identify and demonstrate a universal mechanism for terminating spiral waves in
excitable media using an established topological framework. This mechanism dictates …
excitable media using an established topological framework. This mechanism dictates …
Optogenetic termination of cardiac arrhythmia: mechanistic enlightenment and therapeutic application?
Optogenetic methods enable selective de-and hyperpolarization of cardiomyocytes
expressing light-sensitive proteins within the myocardium. By using light, this technology …
expressing light-sensitive proteins within the myocardium. By using light, this technology …
Excitation and injury of adult ventricular cardiomyocytes by nano-to millisecond electric shocks
Intense electric shocks of nanosecond (ns) duration can become a new modality for more
efficient but safer defibrillation. We extended strength-duration curves for excitation of …
efficient but safer defibrillation. We extended strength-duration curves for excitation of …