There is growing interest in using fluorescence imaging instruments to guide surgery, and
the leading options for open-field imaging are reviewed here. While the clinical fluorescence …

A lack of accepted standards and standardized phantoms suitable for the technical
validation of biophotonic instrumentation hinders the reliability and reproducibility of its …

Background Tumour-targeted fluorescence imaging has the potential to advance current
practice of oncological surgery by selectively highlighting malignant tissue during surgery …

The emerging clinical use of targeted fluorescent agents heralds a shift in intraoperative
imaging practices that overcome the limitations of human vision. However, in contrast to …

Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-
care” medical imaging modality that can potentially provide the sensitivity of nuclear …

Molecular image-guided surgery has the potential for translating the tools of molecular
pathology to real-time guidance in surgery. As a whole, there are incredibly positive …

Surgical resection is a mainstay treatment for solid tumors. Yet, methods to distinguish
malignant from healthy tissue are primarily limited to tactile and visual cues as well as the …

The lymphatic circulatory system has diverse functions in lipid absorption, fluid homeostasis,
and immune surveillance and responds dynamically when presented with infection …

Purpose: The aims of this review are to determine the feasibility of near-infrared
fluorescence (NIRF) angiography in anastomotic colorectal surgery and to determine the …

Significance: Expanded use of fluorescence-guided surgery with devices approved for use
with indocyanine green (ICG) has led to a range of commercial systems available. There is a …