[HTML][HTML] Review of toluene action: clinical evidence, animal studies and molecular targets
SL Cruz, MT Rivera-García… - Journal of drug and …, 2014 - ncbi.nlm.nih.gov
It has long been known that individuals will engage in voluntary inhalation of volatile
solvents for their rewarding effects. However, research into the neurobiology of these agents …
solvents for their rewarding effects. However, research into the neurobiology of these agents …
Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts
The developing nervous system is particularly vulnerable to chemical insults. Exposure to
chemicals can result in neurobehavioural alterations, and these have been used as …
chemicals can result in neurobehavioural alterations, and these have been used as …
Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress
SA Perrine, AL Eagle, SA George, K Mulo… - Behavioural Brain …, 2016 - Elsevier
Appropriate animal models of posttraumatic stress disorder (PTSD) are needed because
human studies remain limited in their ability to probe the underlying neurobiology of PTSD …
human studies remain limited in their ability to probe the underlying neurobiology of PTSD …
Ketamine reverses stress-induced depression-like behavior and increased GABA levels in the anterior cingulate: an 11.7 T 1H-MRS study in rats
SA Perrine, F Ghoddoussi, MS Michaels… - Progress in Neuro …, 2014 - Elsevier
Gamma-aminobutyric acid (GABA) is the major inhibitory amino acid neurotransmitter in the
brain and is primarily responsible for modulating excitatory tone. Clinical neuroimaging …
brain and is primarily responsible for modulating excitatory tone. Clinical neuroimaging …
Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice
CJ Davidson, JH Hannigan, SA Perrine… - Neurotoxicology and …, 2024 - Elsevier
Currently, there is a gap in understanding the neurobiological impact early adolescent
toluene exposure has on subsequent actions of other drugs. Adolescent (PND 28–32) male …
toluene exposure has on subsequent actions of other drugs. Adolescent (PND 28–32) male …
Effect of acute exposure to toluene on cortical excitability, neuroplasticity, and motor learning in healthy humans
F Yavari, C van Thriel, MA Nitsche, MF Kuo - Archives of toxicology, 2018 - Springer
Toluene is a well-known neurotoxic organic solvent and a major component of many
industrial and commercial products such as adhesives, paint thinners and gasoline. Many …
industrial and commercial products such as adhesives, paint thinners and gasoline. Many …
Applications of high‐resolution magic angle spinning MRS in biomedical studies I—cell line and animal models
E Kaebisch, TL Fuss, LA Vandergrift… - NMR in …, 2017 - Wiley Online Library
High‐resolution magic angle spinning (HRMAS) MRS allows for direct measurements of non‐
liquid tissue and cell specimens to present valuable insights into the cellular metabolisms of …
liquid tissue and cell specimens to present valuable insights into the cellular metabolisms of …
Toluene inhalation in adolescent rats reduces flexible behaviour in adulthood and alters glutamatergic and GABAergic signalling
TM Furlong, JR Duncan, LH Corbit… - Journal of …, 2016 - Wiley Online Library
Toluene is a commonly abused inhalant that is easily accessible to adolescents. Despite the
increasing incidence of use, our understanding of its long‐term impact remains limited …
increasing incidence of use, our understanding of its long‐term impact remains limited …
Environmental enrichment reverses memory impairment induced by toluene in mice
S Montes, R del Carmen Solís-Guillén… - Neurotoxicology and …, 2017 - Elsevier
Toluene is the main component of a variety of inhalants that are used for intoxication
purposes. Alterations in memory have been reported in inhalant users; however, it is unclear …
purposes. Alterations in memory have been reported in inhalant users; however, it is unclear …
Short-and long-term effects of chronic toluene exposure on recognition memory in adolescent and adult male Wistar rats
MG Zhvania, N Pochkhidze, M Dashniani, Y Tizabi… - Brain Research …, 2022 - Elsevier
Abuse of toluene-containing volatile inhalants, particularly among youth, is of significant
medical and social concern worldwide. Teenagers constitute the most abundant users of …
medical and social concern worldwide. Teenagers constitute the most abundant users of …