Human embryonic stem cells have been defined as self-renewing cells that can give rise to
many types of cells of the body. How and whether these cells can be manipulated to replace …

The potential for the formation of teratomas or other neoplasms is a major safety roadblock
to clinical application of pluripotent stem cell therapies. Preclinical assessment of the risk of …

Cell replacement therapy is a promising approach for the treatment of cardiac diseases, but
is challenged by a limited supply of appropriate cells. We have investigated whether …

Human embryonic stem cells (hESCs) randomly differentiate into multiple cell types during
embryoid body (EB) development. To date, characterization of specific factors capable of …

Background. Fetal membranes are tissues of particular interest for several reasons,
including their role in preventing rejection of the fetus and their early embryologic origin …

Previous studies have shown that prolonged propagation of undifferentiated human
embryonic stem cells (hESCs) requires conditioned medium from mouse embryonic feeders …

Human embryonic stem (ES) cell lines that have the ability to self‐renew and differentiate
into specific cell types have been established. The molecular mechanisms for self‐renewal …

Human embryonic stem (hES) cells hold promise for generating an unlimited supply of cells
for replacement therapies. To characterize hES cells at the molecular level, we obtained …

Human embryonic stem cells (hESCs) are envisioned to be a major source for cell‐based
therapies. Efforts to overcome rejection of hESCs include nuclear transfer and collection of …

The derivation of human embryonic stem (hES) cells establishes a new avenue to approach
many issues in human biology and medicine for the first time. To meet the increased …