Defects and defect engineering in Soft Matter

A Jangizehi, F Schmid, P Besenius, K Kremer… - Soft Matter, 2020 - pubs.rsc.org
Soft matter covers a wide range of materials based on linear or branched polymers, gels and
rubbers, amphiphilic (macro) molecules, colloids, and self-assembled structures. These …

Engineering heterogeneity of precision nanoparticles for biomedical delivery and therapy

D Zheng, K Yang, Z Nie - View, 2021 - Wiley Online Library
Nanoparticle (NP)‐based vehicles are attractive for biomedical delivery and therapy, owing
to improved therapeutic efficiency and reduced adverse effects compared to free drugs …

Janus magnetic‐plasmonic nanoparticles for magnetically guided and thermally activated cancer therapy

A Espinosa, J Reguera, A Curcio, Á Muñoz‐Noval… - Small, 2020 - Wiley Online Library
Progress of thermal tumor therapies and their translation into clinical practice are limited by
insufficient nanoparticle concentration to release therapeutic heating at the tumor site after …

Photo-responsive self-assembly of plasmonic magnetic Janus nanoparticles

M Niehues, S Engel, BJ Ravoo - Langmuir, 2021 - ACS Publications
Stimuli-responsive self-assembly of nanoparticles is a versatile approach for the bottom-up
fabrication of adaptive and functional nanomaterials. For this purpose, anisotropic building …

Computational investigation on lipid bilayer disruption induced by amphiphilic Janus nanoparticles: combined effect of Janus balance and charged lipid concentration

D Nguyen, J Wu, P Corrigan, Y Li - Nanoscale, 2023 - pubs.rsc.org
Janus nanoparticles (NPs) with charged/hydrophobic compartments have garnered
attention for their potential antimicrobial activity. These NPs have been shown to disrupt lipid …

Antibacterial Activity of Amphiphilic Janus Nanoparticles Enhanced by Polycationic Ligands

JT Wiemann, D Nguyen, S Bhattacharyya… - ACS Applied Nano …, 2023 - ACS Publications
The rapid rise of antibiotic resistance has become a critical global health concern,
necessitating the development of alternative treatments, such as antibacterial nanoparticles …

Membrane poration, wrinkling, and compression: deformations of lipid vesicles induced by amphiphilic Janus nanoparticles

JT Wiemann, Z Shen, H Ye, Y Li, Y Yu - Nanoscale, 2020 - pubs.rsc.org
Building upon our previous studies on interactions of amphiphilic Janus nanoparticles with
glass-supported lipid bilayers, we study here how these Janus nanoparticles perturb the …

Targeting the Weak Spot: Preferential Disruption of Bacterial Poles by Janus Nanoparticles

D Nguyen, S Bhattacharyya, H Richman, Y Yu, Y Li - Nano Letters, 2024 - ACS Publications
The interaction between nanoparticles (NPs) and bacterial cell envelopes is crucial for
designing effective antibacterial materials against multi-drug-resistant pathogens. However …

Two sides of the coin: synthesis and applications of Janus particles

Y Li, F Liu, S Demirci, UK Dey, T Rawah, A Chaudary… - Nanoscale, 2025 - pubs.rsc.org
Named after the two-faced Roman god, Janus particles are defined by their distinct dual
chemical compositions on a single particle. Research on micron-sized Janus particles has …

Atomistic simulations on interactions between amphiphilic Janus nanoparticles and lipid bilayers: Effects of lipid ordering and leaflet asymmetry

L Ou, V Corradi, DP Tieleman… - The Journal of Physical …, 2020 - ACS Publications
Amphiphilic Janus nanoparticles, which are hydrophilic on one-half of the particle surface
and hydrophobic on the other half, are ideal carrier candidates for drug delivery due to their …