Mucosal immune responses to infection and vaccination in the respiratory tract
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …
laboratories all over the world generated a huge amount of data describing the prototypical …
The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update
SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …
Pathogenesis and mechanisms of SARS-CoV-2 infection in the intestine, liver, and pancreas
Z Khreefa, MT Barbier, AR Koksal, G Love, L Del Valle - Cells, 2023 - mdpi.com
The novel coronavirus, SARS-CoV-2, rapidly spread worldwide, causing an ongoing global
pandemic. While the respiratory system is the most common site of infection, a significant …
pandemic. While the respiratory system is the most common site of infection, a significant …
Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace
Tissues are highly complicated with spatial heterogeneity in gene expression. However, the
cutting-edge single-cell RNA-seq technology eliminates the spatial information of individual …
cutting-edge single-cell RNA-seq technology eliminates the spatial information of individual …
COVID-19 immunobiology: lessons learned, new questions arise
A Kaklamanos, K Belogiannis, P Skendros… - Frontiers in …, 2021 - frontiersin.org
There is strong evidence that COVID-19 pathophysiology is mainly driven by a
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …
Mild and asymptomatic COVID-19 convalescents present long-term endotype of immunosuppression associated with neutrophil subsets possessing regulatory …
I Siemińska, K Węglarczyk, M Surmiak… - Frontiers in …, 2021 - frontiersin.org
The SARS-CoV-2 infection [coronavirus disease 2019 (COVID-19)] is associated with
severe lymphopenia and impaired immune response, including expansion of myeloid cells …
severe lymphopenia and impaired immune response, including expansion of myeloid cells …
The immune response as a double‐edged sword: The lesson learnt during the COVID‐19 pandemic
The COVID‐19 pandemic has represented an unprecedented challenge for the humanity,
and scientists around the world provided a huge effort to elucidate critical aspects in the fight …
and scientists around the world provided a huge effort to elucidate critical aspects in the fight …
Rationale of using the dual chemokine receptor CCR2/CCR5 inhibitor cenicriviroc for the treatment of COVID-19
Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), has created a global pandemic infecting over 230 million …
Coronavirus 2 (SARS-CoV-2), has created a global pandemic infecting over 230 million …
Spleen tyrosine kinase inhibition restores myeloid homeostasis in COVID-19
G Wigerblad, SA Warner, MJ Ramos-Benitez… - Science …, 2023 - science.org
Spleen tyrosine kinase (SYK) is a previously unidentified therapeutic target that inhibits
neutrophil and macrophage activation in coronavirus disease 2019 (COVID-19) …
neutrophil and macrophage activation in coronavirus disease 2019 (COVID-19) …