Alzheimer's and Parkinson's disease therapies in the clinic
P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …
neurodegenerative diseases, affecting millions and costing billions each year in the United …
Sex differences in hippocampal cognition and neurogenesis
S Yagi, LAM Galea - Neuropsychopharmacology, 2019 - nature.com
Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …
OASIS-3: longitudinal neuroimaging, clinical, and cognitive dataset for normal aging and Alzheimer disease
PJ LaMontagne, TLS Benzinger, JC Morris, S Keefe… - medrxiv, 2019 - medrxiv.org
ABSTRACT OASIS-3 is a compilation of MRI and PET imaging and related clinical data for
1098 participants who were collected across several ongoing studies in the Washington …
1098 participants who were collected across several ongoing studies in the Washington …
Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET
β-Amyloid plaques and tau-containing neurofibrillary tangles are the two neuropathological
hallmarks of Alzheimer's disease (AD) and are thought to play crucial roles in a …
hallmarks of Alzheimer's disease (AD) and are thought to play crucial roles in a …
FreeSurfer
B Fischl - Neuroimage, 2012 - Elsevier
FreeSurfer is a suite of tools for the analysis of neuroimaging data that provides an array of
algorithms to quantify the functional, connectional and structural properties of the human …
algorithms to quantify the functional, connectional and structural properties of the human …
Relationships of dietary patterns, foods, and micro-and macronutrients with Alzheimer's disease and late-life cognitive disorders: a systematic review
V Solfrizzi, C Custodero, M Lozupone… - Journal of …, 2017 - content.iospress.com
In the last decade, the association between diet and cognitive function or dementia has
been largely investigated. In the present article, we systematically reviewed observational …
been largely investigated. In the present article, we systematically reviewed observational …
Within-subject template estimation for unbiased longitudinal image analysis
Longitudinal image analysis has become increasingly important in clinical studies of normal
aging and neurodegenerative disorders. Furthermore, there is a growing appreciation of the …
aging and neurodegenerative disorders. Furthermore, there is a growing appreciation of the …
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
CR Jack, DS Knopman, WJ Jagust… - The lancet …, 2013 - thelancet.com
In 2010, we put forward a hypothetical model of the major biomarkers of Alzheimer's disease
(AD). The model was received with interest because we described the temporal evolution of …
(AD). The model was received with interest because we described the temporal evolution of …
[HTML][HTML] Alzheimer's disease profiled by fluid and imaging markers: tau PET best predicts cognitive decline
For early detection of Alzheimer's disease, it is important to find biomarkers with predictive
value for disease progression and clinical manifestations, such as cognitive decline …
value for disease progression and clinical manifestations, such as cognitive decline …
[HTML][HTML] Neuroimaging biomarkers for Alzheimer's disease
F Márquez, MA Yassa - Molecular neurodegeneration, 2019 - Springer
Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …