Ferroptosis, a new non-necrotizing programmed cell death (PCD), is driven by iron-
dependent phospholipid peroxidation. Ferroptosis plays a key role in secondary traumatic …

In recent years, three emerging cell deaths, ferroptosis, necroptosis and pyroptosis, have
gradually attracted everyone's attention, and they also play an important role in the …

Ferroptosis and iron-related redox imbalance aggravate traumatic brain injury (TBI)
outcomes. NRF2 is the predominant transcription factor regulating oxidative stress and …

Although traumatic brain injury (TBI) is a common cause of death and disability worldwide,
there is currently a lack of effective therapeutic drugs and targets. To reveal the complex …

The current lack of understanding about how nanocarriers cross the blood‐brain barrier
(BBB) in the healthy and injured brain is hindering the clinical translation of nanoscale brain …

Necroptosis, a regulated form of cell death, is involved in the genesis and development of
various life-threatening diseases, including cancer, neurological disorders, cardiac …

Excessive iron released by hemoglobin and necrotic tissues is the predominant factor that
aggravates the outcome of traumatic brain injury (TBI). Regulating the levels of iron and its …

Ferroptosis is morphologically characterized by shrunken mitochondria and biochemically
characterized by iron overload, lipid peroxidation and lipid reactive oxygen species (ROS) …

Traumatic brain injury (TBI) has been recognized as a serious public health issue and a key
contributor to disability and death, with a huge economic burden worldwide. Hydrogen …

In the last few years, necroptosis, a recently described type of cell death, has been reported
to play an important role in the development of various brain pathologies. Necroptosis is a …