Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion
NMR and MRI the mainstay of most studies seeking to resolve microstructural information in …

Principles from multidimensional NMR spectroscopy, and in particular solid-state NMR, have
recently been transferred to the field of diffusion MRI, offering non-invasive characterization …

Mapping mean axon diameter and intra-axonal volume fraction may have significant clinical
potential because nerve conduction velocity is directly dependent on axon diameter, and …

Purpose Filter exchange imaging (FEXI) is sensitive to the rate of diffusional water
exchange, which depends, eg, on the cell membrane permeability. The aim was to optimize …

Abstracts Blood-brain barrier (BBB) impairment is an important pathophysiological process
in Alzheimer's disease (AD) and a potential biomarker for early diagnosis of AD. However …

Transmembrane water exchange, including intra-to-extravascular and intra-to-extracellular
ones, are potential biomarkers in the diagnosis and understanding of cancers, brain …

The dependence of the diffusion MRI signal on the diffusion time carries signatures of
restricted diffusion and exchange. Here we seek to highlight these signatures in the human …

For its size, the brain is the most metabolically active organ in the body. Most of its energy
demand is used to maintain stable homeostatic physiological conditions. Altered …

Water transport across cell membranes can be measured non-invasively with diffusion NMR.
We present a method to quantify the intracellular lifetime of water in cell suspensions with …

Purpose Filter exchange imaging (FEXI) and diffusion time (t)‐dependent diffusion kurtosis
imaging (DKI (t)) are both sensitive to water exchange between tissue compartments. The …