Respiratory syncytial virus infection and novel interventions
AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …
young children and older adults has gained increased recognition in recent years. Recent …
Vitamin D for the prevention of disease: an Endocrine Society clinical practice guideline
MB Demay, AG Pittas, DD Bikle, DL Diab… - The Journal of …, 2024 - academic.oup.com
Background Numerous studies demonstrate associations between serum concentrations of
25-hydroxyvitamin D (25 [OH] D) and a variety of common disorders, including …
25-hydroxyvitamin D (25 [OH] D) and a variety of common disorders, including …
Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants
B Kampmann, SA Madhi, I Munjal… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …
[HTML][HTML] Nirsevimab for prevention of hospitalizations due to RSV in infants
SB Drysdale, K Cathie, F Flamein, M Knuf… - … England Journal of …, 2023 - Mass Medical Soc
Background The safety of the monoclonal antibody nirsevimab and the effect of nirsevimab
on hospitalizations for respiratory syncytial virus (RSV)–associated lower respiratory tract …
on hospitalizations for respiratory syncytial virus (RSV)–associated lower respiratory tract …
Epidemiology of respiratory syncytial virus in children younger than 5 years in England during the COVID-19 pandemic, measured by laboratory, clinical, and …
M Bardsley, RA Morbey, HE Hughes… - The Lancet Infectious …, 2023 - thelancet.com
Background Seasonal epidemics of respiratory syncytial virus (RSV) cause a clinically
significant burden of disease among young children. Non-pharmaceutical interventions …
significant burden of disease among young children. Non-pharmaceutical interventions …
Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with …
Background In a phase 2b trial and the phase 3 MELODY trial, nirsevimab, an extended half-
life, monoclonal antibody against respiratory syncytial virus (RSV), protected healthy infants …
life, monoclonal antibody against respiratory syncytial virus (RSV), protected healthy infants …
RSV prefusion f protein–based maternal vaccine—preterm birth and other outcomes
I Dieussaert, J Hyung Kim, S Luik, C Seidl… - … England Journal of …, 2024 - Mass Medical Soc
Background Vaccination against respiratory syncytial virus (RSV) during pregnancy may
protect infants from RSV disease. Efficacy and safety data on a candidate RSV prefusion F …
protect infants from RSV disease. Efficacy and safety data on a candidate RSV prefusion F …
The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study
JG Wildenbeest, MN Billard, RP Zuurbier… - The Lancet …, 2023 - thelancet.com
Background Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants.
The burden of RSV infection in healthy term infants has not yet been established. Accurate …
The burden of RSV infection in healthy term infants has not yet been established. Accurate …
Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study
C Rosas-Salazar, T Chirkova, T Gebretsadik… - The Lancet, 2023 - thelancet.com
Background Early-life severe respiratory syncytial virus (RSV) infection has been associated
with the onset of childhood wheezing illnesses. However, the relationship between RSV …
with the onset of childhood wheezing illnesses. However, the relationship between RSV …
Durability of neutralizing RSV antibodies following nirsevimab administration and elicitation of the natural immune response to RSV infection in infants
D Wilkins, Y Yuan, Y Chang, AA Aksyuk, BS Núñez… - Nature Medicine, 2023 - nature.com
Nirsevimab is an extended half-life monoclonal antibody specific for the prefusion
conformation of the respiratory syncytial virus (RSV) F protein, which has been studied in …
conformation of the respiratory syncytial virus (RSV) F protein, which has been studied in …