Recent trends in biocatalysis
D Yi, T Bayer, CPS Badenhorst, S Wu… - Chemical Society …, 2021 - pubs.rsc.org
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …
Cytochrome P450 enzymes in fungal natural product biosynthesis
X Zhang, J Guo, F Cheng, S Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2015 to the end of 2020 Fungal-derived polyketides, non-ribosomal peptides,
terpenoids and their hybrids contribute significantly to the chemical space of total natural …
terpenoids and their hybrids contribute significantly to the chemical space of total natural …
De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories
Isoflavonoids comprise a class of plant natural products with great nutraceutical,
pharmaceutical and agricultural significance. Their low abundance in nature and structural …
pharmaceutical and agricultural significance. Their low abundance in nature and structural …
Marine drugs: Biology, pipelines, current and future prospects for production
The marine environment is a huge reservoir of biodiversity and represents an excellent
source of chemical compounds, some of which have large economical values. In the urgent …
source of chemical compounds, some of which have large economical values. In the urgent …
Recent advances in the biosynthesis strategies of nitrogen heterocyclic natural products
B Gao, B Yang, X Feng, C Li - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2015 to 2020 Nitrogen heterocyclic natural products (NHNPs) are primary or
secondary metabolites containing nitrogen heterocyclic (N-heterocyclic) skeletons. Due to …
secondary metabolites containing nitrogen heterocyclic (N-heterocyclic) skeletons. Due to …
Screening non-conventional yeasts for acid tolerance and engineering Pichia occidentalis for production of muconic acid
Saccharomyces cerevisiae is a workhorse of industrial biotechnology owing to the
organism's prominence in alcohol fermentation and the suite of sophisticated genetic tools …
organism's prominence in alcohol fermentation and the suite of sophisticated genetic tools …
De novo biosynthesis of berberine and halogenated benzylisoquinoline alkaloids in Saccharomyces cerevisiae
Berberine is an extensively used pharmaceutical benzylisoquinoline alkaloid (BIA) derived
from plants. Microbial manufacturing has emerged as a promising approach to source …
from plants. Microbial manufacturing has emerged as a promising approach to source …
Biosynthesis and synthetic biology of psychoactive natural products
Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …
structural complexity displayed by such molecules confers diverse biological activities of …
Biosynthesis of tetrahydropapaverine and semisynthesis of papaverine in yeast
Tetrahydropapaverine (THP) and papaverine are plant natural products with clinically
significant roles. THP is a precursor in the production of the drugs atracurium and …
significant roles. THP is a precursor in the production of the drugs atracurium and …
Construction of an l-Tyrosine Chassis in Pichia pastoris Enhances Aromatic Secondary Metabolite Production from Glycerol
R Kumokita, T Bamba, K Inokuma, T Yoshida… - ACS Synthetic …, 2022 - ACS Publications
Bioactive plant-based secondary metabolites such as stilbenoids, flavonoids, and
benzylisoquinoline alkaloids (BIAs) are produced from l-tyrosine (l-Tyr) and have a wide …
benzylisoquinoline alkaloids (BIAs) are produced from l-tyrosine (l-Tyr) and have a wide …