Primary open-angle glaucoma

RN Weinreb, PT Khaw - The lancet, 2004 - thelancet.com
Primary open-angle glaucoma is a progressive optic neuropathy and, perhaps, the most
common form of glaucoma. Because the disease is treatable, and because the visual …

Steroid-induced glaucoma: Epidemiology, pathophysiology, and clinical management

G Roberti, F Oddone, L Agnifili, A Katsanos… - Survey of …, 2020 - Elsevier
Glucocorticoids are a class of anti-inflammatory drugs commonly used to treat various ocular
and systemic conditions. Although the role of glucocorticoids in the treatment of numerous …

Primary open-angle glaucoma

YH Kwon, JH Fingert, MH Kuehn… - New England Journal …, 2009 - Mass Medical Soc
Primary Open-Angle Glaucoma | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Identification of a gene that causes primary open angle glaucoma

EM Stone, JH Fingert, WLM Alward, TD Nguyen… - Science, 1997 - science.org
Glaucoma is a major cause of blindness and is characterized by progressive degeneration
of the optic nerve and is usually associated with elevated intraocular pressure. Analyses of …

Genetic risk of primary open-angle glaucoma: population-based familial aggregation study

RCW Wolfs, CCW Klaver, RS Ramrattan… - Archives of …, 1998 - jamanetwork.com
Objectives To study familial aggregation of primary open-angle glaucoma in a general
population and to determine the absolute and relative risks for first-degree relatives …

CRISPR-Cas9–based treatment of myocilin-associated glaucoma

A Jain, G Zode, RB Kasetti, FA Ran… - Proceedings of the …, 2017 - National Acad Sciences
Primary open-angle glaucoma (POAG) is a leading cause of irreversible vision loss
worldwide, with elevated intraocular pressure (IOP) a major risk factor. Myocilin (MYOC) …

The clinical effectiveness and cost-effectiveness of screening for open angle glaucoma: a systematic review and economic evaluation.

JM Burr, G Mowatt, R Hernández… - Health technology …, 2007 - researchonline.lshtm.ac.uk
OBJECTIVES: To assess whether open angle glaucoma (OAG) screening meets the UK
National Screening Committee criteria, to compare screening strategies with case finding, to …

Identification of Three Different Truncating Mutations in Cytochrome P4501B1 (CYP1B1) as the Principal Cause of Primary Congenital Glaucoma (Buphthalmos) in …

I Stoilov, AN Akarsu, M Sarfarazi - Human molecular genetics, 1997 - academic.oup.com
Primary congenital glaucoma (Buphthalmos) is an autosomal recessive eye disorder,
postulated to result from developmental defects in the anterior eye segment. Previously, we …

Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

JH Fingert, E Héon, JM Liebmann… - Human molecular …, 1999 - academic.oup.com
Abstract A glaucoma locus, GLC1A, was identified previously on chromosome 1q. A gene
within this locus (encoding the protein myocilin) subsequently was shown to harbor …

Steroid-induced iatrogenic glaucoma

MR Razeghinejad, LJ Katz - Ophthalmic research, 2012 - karger.com
Steroids in susceptible individuals can cause a clinical condition similar to primary open-
angle glaucoma. Five percent of the population are high steroid responders and develop an …