The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

CD8+ T‐cell deficiency is a feature of many chronic autoimmune diseases, including
multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, Sjögren′ s …

It has been 12 years since the Allele Frequency Net Database (AFND; http://www.
allelefrequencies. net) was first launched, providing the scientific community with an online …

Motivation: The human leukocyte antigen (HLA) gene cluster plays a crucial role in adaptive
immunity and is thus relevant in many biomedical applications. While next-generation …

The allele frequency net database (http://www. allelefrequencies. net) is an online repository
that contains information on the frequencies of immune genes and their corresponding …

The HLA region encodes several molecules that play key roles in the immune system.
Strong association between the HLA region and autoimmune disease (AID) has been …

Celiac disease (CD) is a primarily digestive systemic disease triggered and maintained by
the ingestion of gluten in the diet. Its has a wide clinical spectrum of manifestations …

Biologic drugs have greatly improved treatment outcomes of inflammatory joint diseases, but
a substantial proportion of patients either do not respond to treatment or lose response over …

The immune system has evolved to protect the host from microbial infection; nevertheless, a
breakdown in the immune system often results in infection, cancer, and autoimmune …

With multiple genome-wide association studies (GWAS) performed across autoimmune
diseases, there is a great opportunity to study the homogeneity of genetic architectures …