Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis

C Tan, Q Yan, Y Ma, J Fang, Y Yang - Frontiers in Neurology, 2022 - frontiersin.org
Depression is a worldwide disease causing severe disability, morbidity, and mortality.
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …

[HTML][HTML] The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches

A Varesi, LIM Campagnoli, S Chirumbolo… - Pharmacological …, 2023 - Elsevier
Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …

Prebiotic and probiotic modulation of the microbiota–gut–brain axis in depression

DE Radford-Smith, DC Anthony - Nutrients, 2023 - mdpi.com
Emerging evidence demonstrates that alterations to the gut microbiota can affect mood,
suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of …

Neurobiology and systems biology of stress resilience

R Kalisch, SJ Russo, MB Müller - Physiological Reviews, 2024 - journals.physiology.org
Stress resilience is the phenomenon that some people maintain their mental health despite
exposure to adversity or show only temporary impairments followed by quick recovery …

Effectiveness of probiotic/prebiotic/synbiotic treatments on anxiety: a systematic review and meta-analysis of randomized controlled trials

Z Zhao, G Xiao, J Xia, H Guo, X Yang, Q Jiang… - Journal of affective …, 2023 - Elsevier
Background Anxiety can adversely affect human well-being. This meta-analysis aimed to
evaluate the effects of interventions that alter the gut microbes (including probiotics …

The role of probiotics and their metabolites in the treatment of depression

ME Jach, A Serefko, A Szopa, E Sajnaga, H Golczyk… - Molecules, 2023 - mdpi.com
Depression is a common and complex mental and emotional disorder that causes disability,
morbidity, and quite often mortality around the world. Depression is closely related to several …

Depression-associated gut microbes, metabolites and clinical trials

M Wang, Z Song, S Lai, F Tang, L Dou… - Frontiers in …, 2024 - frontiersin.org
Depression is one of the most prevalent mental disorders today. Over the past decade, there
has been considerable attention given to the field of gut microbiota associated with …

An insight into the functional alterations in the gut microbiome of healthy adults in response to a multi-strain probiotic intake: a single arm open label trial

A Rodenes-Gavidia, A Lamelas, S Bloor… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Probiotic supplements, by definition, provide a benefit to the host, but few
studies have investigated the effect of probiotic supplements in healthy adult populations …

Bifidobacterium longum 1714 improves sleep quality and aspects of well-being in healthy adults: a randomized, double-blind, placebo-controlled clinical trial

E Patterson, HTT Tan, D Groeger, M Andrews… - Scientific Reports, 2024 - nature.com
Stress and sleep are linked with overall well-being. Bifidobacterium longum 1714 has been
shown to influence stress responses and modulate neural responses during social stress …

[HTML][HTML] Live or heat-killed probiotic administration reduces anxiety and central cytokine expression in BALB/c mice, but differentially alters brain neurotransmitter gene …

KW Chan, J Hebert, D Radford-Smith, DC Anthony… - …, 2023 - Elsevier
While the potential for probiotic supplements to act as adjunctive treatments for mood
disorders has been widely demonstrated, the precise mode of action remains unclear. To …