Radiochemistry for positron emission tomography
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …
Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions
X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …
quantitative information about function and metabolism in biological processes in vivo for …
[HTML][HTML] Recent developments on PET radiotracers for TSPO and their applications in neuroimaging
The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is predominately localized to the outer mitochondrial membrane in …
benzodiazepine receptor, is predominately localized to the outer mitochondrial membrane in …
18F-Fluorination: Challenge and Opportunity for Organic Chemists
R Halder, T Ritter - The Journal of Organic Chemistry, 2021 - ACS Publications
18F-fluorination is an important and growing field in organic synthesis that has attracted
many chemists in the recent past. Here we present our own, biased perspective with a focus …
many chemists in the recent past. Here we present our own, biased perspective with a focus …
Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands
NJ Taylor, E Emer, S Preshlock… - Journal of the …, 2017 - ACS Publications
Molecules labeled with fluorine-18 (18F) are used in positron emission tomography to
visualize, characterize and measure biological processes in the body. Despite recent …
visualize, characterize and measure biological processes in the body. Despite recent …
Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF
KJ Makaravage, AF Brooks, AV Mossine… - Organic …, 2016 - ACS Publications
A copper-mediated nucleophilic radiofluorination of aryl-and vinylstannanes with [18F] KF is
described. This method is fast, uses commercially available reagents, and is compatible with …
described. This method is fast, uses commercially available reagents, and is compatible with …
Divergent C (sp 2)–H arylation of heterocycles via organic photoredox catalysis
J Ren, C Pi, X Cui, Y Wu - Green Chemistry, 2022 - pubs.rsc.org
Introducing aryl moieties into heterocyclic scaffolds is a key step in the syntheses of natural
products, drugs, and functional materials. Herein, we describe an unprecedented …
products, drugs, and functional materials. Herein, we describe an unprecedented …
Recent progress in the application of iodonium ylides in organic synthesis
X Mi, C Pi, W Feng, X Cui - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Iodonium ylides have attracted considerable attention due to their unique properties and
numerous applications as versatile and sustainable reagents in organic synthesis …
numerous applications as versatile and sustainable reagents in organic synthesis …
Rhodium(III)‐Catalyzed Divergent C−H Functionalization of N‐Aryl Amidines with Iodonium Ylides: Access to Carbazolones and Zwitterionic Salts
J Ren, L Yang, C Pi, X Cui, Y Wu - Advanced Synthesis & …, 2023 - Wiley Online Library
We described an Rhodium (III)‐catalyzed divergent C− H bond functionalization of N‐aryl
amidines with iodonium ylides. Carbazolones and zwitterionic salts were diversely …
amidines with iodonium ylides. Carbazolones and zwitterionic salts were diversely …
Cu-Mediated C–H 18F-Fluorination of Electron-Rich (Hetero)arenes
MS McCammant, S Thompson, AF Brooks… - Organic …, 2017 - ACS Publications
This communication describes a method for the nucleophilic radiofluorination of electron-
rich arenes. The reaction involves the initial C (sp2)–H functionalization of an electron-rich …
rich arenes. The reaction involves the initial C (sp2)–H functionalization of an electron-rich …