Perianal fistulising Crohn's disease is an aggressive disease phenotype that can have a
substantial detrimental impact on patients' quality of life. Current biological understanding of …

Background The management of perianal Crohn's disease is difficult. A wide variety of
treatment options exist although few are evidence based. Methods A search was conducted …

The transmural inflammation characteristic of Crohn's disease predisposes patients to the
formation of fistulas. Up to 50% of patients with Crohn's disease are affected by fistulas …

Pelvic magnetic resonance (MR) imaging is currently the standard for imaging perianal
Crohn disease. Perianal fistulas are a leading cause of patient morbidity because closure …

Aim There is a requirement of an expansive and up to date review of surgical management
of inflammatory bowel disease (IBD) that can dovetail with the medical guidelines produced …

Patients with Crohn's disease commonly undergo surgery during their lifetime. Indications
for surgical intervention include obstruction, intra-abdominal or perianal abscess …

Abstract Background and Aims Rectal resection in inflammatory bowel disease [IBD] is
frequently complicated by disturbed perineal wound healing. Close rectal dissection, where …

Background Pouch failure occurs in up to 10 per cent of patients after ileal pouch–anal
anastomosis (IPAA). The aims of this study were to determine the reasons for pouch excision …

Crohn's disease remains an incurable chronic illness with frequent relapses. Management
of anorectal manifestations can pose an enormous challenge, as seen by the myriad of …

PURPOSE:: Restorative proctocolectomy is the elective surgical procedure of choice for
ulcerative colitis and familial adenomatous polyposis. Most patients have a satisfactory …