Molecular dynamics (MD) simulation is a useful technique to study the interaction between
molecules and how they are affected by various processes and processing conditions. This …

Optimization of the systems for active-targeting drug delivery is a pending task in view of
more directed transport of the active components to neoplastic cells. One of the ways to …

The gastric peptide hormone human PYY3–36 is a target for the development of
therapeutics, especially for treatment of obesity. The conformation and aggregation behavior …

Vitamin B12 also called cobalamin (Cbl) is an important enzymatic cofactor taken up by
mammalian and also by many bacterial cells. Peptide nucleic acid (PNA) is a synthetic DNA …

The synthesis and structural characterization of Co‐(dN) 25‐Cbl (Cbl: cobalamin; dN:
deoxynucleotide) and Co‐(dN) 39‐Cbl, which are organometallic DNA–B12 conjugates with …

The consumption of vitamin B12 (B12), also known as cobalamin, is essential for humans.
B12 is produced naturally by select bacteria and organisms must acquire the vitamin …

Obesity is a global healthissue with nations struggling to deal with itstreatmentand economic
impacts. Modified peptide hormones have already been shown to be effective at improving …

The increasing number of papers in which bioconjugates of oligopeptides and/or amino
acids are present indicates the importance and potential of these constructs. In this chapter …

The development of microbial resistance to common small molecule antibiotics is continuing
to be a thread to modern medicine and drives the search for novel antibiotics for the clinic …