Translating ocular biomechanics into clinical practice: current state and future prospects

MJA Girard, WJ Dupps, M Baskaran… - Current eye …, 2015 - Taylor & Francis
Biomechanics is the study of the relationship between forces and function in living
organisms and is thought to play a critical role in a significant number of ophthalmic …

[HTML][HTML] Biomechanics of the sclera and effects on intraocular pressure

X Jia, J Yu, SH Liao, XC Duan - International journal of …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that glaucoma is a multifactorial neurodegenerative
disease characterized by the loss of retinal ganglion cells (RGC), resulting in gradual and …

Anterior and posterior corneal stroma elasticity assessed using nanoindentation

JM Dias, NM Ziebarth - Experimental eye research, 2013 - Elsevier
Corneal biomechanics is an essential parameter for developing diagnostic and treatment
methods of corneal-related diseases. It is widely accepted that corneal mechanical strength …

Changes in iris stiffness and permeability in primary angle closure glaucoma

SK Panda, RKY Tan, TA Tun, ML Buist… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: To evaluate the biomechanical properties of the iris by evaluating iris movement
during pupil constriction and to compare such properties between healthy and primary angle …

Quantification of iris elasticity using acoustic radiation force optical coherence elastography

Y Zhu, Y Zhang, G Shi, Q Xue, X Han, S Ai, J Shi… - Applied Optics, 2020 - opg.optica.org
Careful quantification of the changes in biomechanical properties of the iris can offer insight
into the pathophysiology of some ocular diseases. However, to date there has not been …

[HTML][HTML] Increased iris stiffness in patients with a history of angle-closure glaucoma: an image-based inverse modeling analysis

AD Pant, P Gogte, V Pathak-Ray… - … & visual science, 2018 - jov.arvojournals.org
Purpose: Previous studies have shown that iris mechanical properties may play a role in the
pathophysiology of primary angle-closure glaucoma (PACG). Such studies, however, were …

Numerical study of aqueous humor flow and iris deformation with pupillary block and the efficacy of laser peripheral iridotomy

JC Cai, YL Chen, YH Cao, A Babenko, X Chen - Clinical Biomechanics, 2022 - Elsevier
Background Disclosing the mechanism of primary angle closure glaucoma with pupillary
block is important to the diagnosis as well as treatments, such as the laser peripheral …

[HTML][HTML] Young's modulus determination of normal and glaucomatous human iris

A Narayanaswamy, MH Nai… - … & visual science, 2019 - tvst.arvojournals.org
Purpose: To evaluate the biomechanical properties (Young's modulus) of normal (control)
and glaucomatous human iris using atomic force microscopy (AFM). Methods: Iris tissue …

An inverse method to determine the mechanical properties of the iris in vivo

K Zhang, X Qian, X Mei, Z Liu - Biomedical engineering online, 2014 - Springer
Background Understanding the mechanical properties of the iris can help to have an insight
into the eye diseases with abnormalities of the iris morphology. Material parameters of the …

A simple basis for determination of the modulus and hydraulic conductivity of human ocular surface using nano-indentation

MV Swain, J Nohava, P Eberwein - Acta biomaterialia, 2017 - Elsevier
This paper presents a simple analysis based upon Darcy's Law and indentation contact
mechanics to determine the effective hydraulic conductivity and elastic modulus of fluid filled …