Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

Transitory phenotypic changes such as the epithelial–mesenchymal transition (EMT) help
embryonic cells to generate migratory descendants that populate new sites and establish …

Glioblastoma remains one of the most lethal types of cancer, and is the most common brain
tumour in adults. In particular, tumour recurrence after surgical resection and radiation …

MicroRNAs (miRNAs) are a set of non-coding small RNA molecules in control of gene
expression at posttranscriptional/translational level. They not only play crucial roles in …

Abstract The EGFR/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway plays prominent roles in
malignant transformation, prevention of apoptosis, drug resistance and metastasis. The …

The neuropilins (Nrps) are multifunctional proteins involved in development, immunity and
cancer. Neuropilin-1 (Nrp1), or its homologue neuropilin-2 (Nrp2), are coreceptors that …

The MYBL2 gene, also known as B-MYB, is essential to regulate vital cellular processes
including cell proliferation, differentiation and DNA repair. Changes in these pathways can …

The molecular underpinnings of aggressive breast cancers remain mainly obscure. Here we
demonstrate that activation of the transcription factor c-Myb is required for the prometastatic …

Epithelial-to-mesenchymal transition (EMT) is essential for embryonic morphogenesis and
wound healing and critical for tumour cell invasion and dissemination. The AP-1 …

The long non-coding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) has been
demonstrated to participate in the deterioration of many types of cancer. However, the …