The locus coeruleus norepinephrine (LC-NE) system plays a broad role in learning and
memory. Here we begin with an overview of the LC-NE system. We then consider how both …

The catecholamines dopamine (DA) and norepinephrine provide an essential modulatory
influence on the working memory and attentional functions of the prefrontal cortex (PFC) …

Abstract α 2-Adrenergic receptors in brain are important presynaptic modulators of central
noradrenergic function (autoreceptors) and postsynaptic mediators of many of the …

Selective 35S‐labeled oligonucleotide probes were designed to sequences of the rat alpha‐
2A (RG20), alpha‐2B (RNG), and alpha‐2C (RG10) adrenoreceptor mRNAs for use in in situ …

The α 2-adrenoceptor was subdivided into three subtypes: α 2A-, α 2B-and α 2C-
adrenoceptors almost ten years ago. Since then, the search has been on to discover and …

• The safety and effectiveness of clonidine hydrochloride (3 to 5 μg/kg per day) were
evaluated in 47 subjects with Gilles de la Tourette's syndrome, aged 7 to 48 years. Twenty …

Aerobic glycolysis occurs during brain activation and is characterized by preferential up‐
regulation of glucose utilization compared with oxygen consumption even though oxygen …

The gene for the human platelet α2-adrenergic receptor has been cloned with
oligonucleotides corresponding to the partial amino acid sequence of the purified receptor …

A review of the available evidence indicates that oc2-adrenoceptors are not a homogeneous
class of receptors, but can be subdivided into several subtypes based on their …

An alpha 2-adrenergic receptor subtype has been cloned from a human kidney cDNA library
using the gene for the human platelet alpha 2-adrenergic receptor as a probe. The deduced …