Radiosynthesis, preclinical, and clinical positron emission tomography studies of carbon-11 labeled endogenous and natural exogenous compounds
The presence of positron emission tomography (PET) centers at most major hospitals
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …
Radiation dose estimates for carbon-11-labelled PET tracers
INTRODUCTION: Carbon-11-labelled positron emission tomography (PET) tracers
commonly used in biomedical research expose subjects to ionising radiation. Dosimetry is …
commonly used in biomedical research expose subjects to ionising radiation. Dosimetry is …
[18F] fluoroestradiol radiation dosimetry in human PET studies
DA Mankoff, LM Peterson, TJ Tewson… - Journal of Nuclear …, 2001 - Soc Nuclear Med
[18F] 16α-fluoroestradiol (FES) is a PET imaging agent useful for the study of estrogen
receptors in breast cancer. We estimated the radiation dosimetry for this tracer using data …
receptors in breast cancer. We estimated the radiation dosimetry for this tracer using data …
Biodistribution and radiation dosimetry of [11C]choline: a comparison between rat and human data
T Tolvanen, T Yli-Kerttula, T Ujula, A Autio… - European journal of …, 2010 - Springer
Abstract Purpose Methyl-11 C-choline ([11 C] choline) is a radiopharmaceutical used for
oncological PET studies. We investigated the biodistribution and biokinetics of [11 C] choline …
oncological PET studies. We investigated the biodistribution and biokinetics of [11 C] choline …
Suggested pathway to assess radiation safety of 11C-labeled PET tracers for first-in-human studies
P Zanotti-Fregonara, RB Innis - European journal of nuclear medicine and …, 2012 - Springer
Dear Sir, Before a new radioactive tracer can be used in humans, many national as well as
local Institutional Radiation Safety Committees often require that a biodistribution study be …
local Institutional Radiation Safety Committees often require that a biodistribution study be …
[图书][B] NeuroPET: positron emission tomography in neuroscience and clinical neurology
K Herholz, P Herscovitch, WD Heiss - 2012 - books.google.com
Positron emission tomography (PET) provides unbiased in vivo measurement of local tracer
activity at very high sensitivity. This is a unique property unmatched by other imaging …
activity at very high sensitivity. This is a unique property unmatched by other imaging …
Human biodistribution and radiation dosimetry of 11C-(R)-PK11195, the prototypic PET ligand to image inflammation
J Hirvonen, A Roivainen, J Virta, S Helin… - European journal of …, 2010 - Springer
Purpose The positron emission tomography (PET) radiotracer 11 C-(R)-PK11195 allows the
in vivo imaging in humans of the translocator protein 18 kDa (TSPO), previously called …
in vivo imaging in humans of the translocator protein 18 kDa (TSPO), previously called …
Radiosynthesis automation, non-human primate biodistribution and dosimetry of K+ channel tracer [11C]3MeO4AP
Abstract Background 4-Aminopyridine (4AP) is a medication for the symptomatic treatment of
multiple sclerosis. Several 4AP-based PET tracers have been developed for imaging …
multiple sclerosis. Several 4AP-based PET tracers have been developed for imaging …
Cardiac metabolic imaging: current imaging modalities and future perspectives
T van de Weijer, EHM Paiman… - Journal of Applied …, 2018 - journals.physiology.org
In this review, current imaging techniques and their future perspectives in the field of cardiac
metabolic imaging in humans are discussed. This includes a range of noninvasive imaging …
metabolic imaging in humans are discussed. This includes a range of noninvasive imaging …
Whole-body biodistribution and estimation of radiation-absorbed doses of the dopamine D1 receptor radioligand 11C-NNC 112 in humans
VL Cropley, M Fujita, JL Musachio, J Hong… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The present study estimated radiation-absorbed doses of the dopamine D1 receptor
radioligand [11C]((+)-8-chloro-5-(7-benzofuranyl)-7-hydroxy-3-methyl-2, 3, 4, 5-tetrahydro-1 …
radioligand [11C]((+)-8-chloro-5-(7-benzofuranyl)-7-hydroxy-3-methyl-2, 3, 4, 5-tetrahydro-1 …