Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
The neuroimmune axis of Alzheimer's disease
Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
INTRODUCTION Myeloid cells are highly heterogeneous, with distinct ontogenies and
immune functions. The diverse role of myeloid populations, including monocytes …
immune functions. The diverse role of myeloid populations, including monocytes …
Transforming the understanding of brain immunity
Contemporary studies have completely changed the view of brain immunity from envisioning
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …
[HTML][HTML] Functional characterization of the dural sinuses as a neuroimmune interface
Despite the established dogma of central nervous system (CNS) immune privilege,
neuroimmune interactions play an active role in diverse neurological disorders. However …
neuroimmune interactions play an active role in diverse neurological disorders. However …
The glymphatic system: a novel component of fundamental neurobiology
LM Hablitz, M Nedergaard - Journal of Neuroscience, 2021 - Soc Neuroscience
Throughout the body, lymphatic fluid movement supports critical functions including
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …
Brain borders at the central stage of neuroimmunology
J Rustenhoven, J Kipnis - Nature, 2022 - nature.com
The concept of immune privilege suggests that the central nervous system is isolated from
the immune system. However, recent studies have highlighted the borders of the central …
the immune system. However, recent studies have highlighted the borders of the central …
Immune responses to stroke: mechanisms, modulation, and therapeutic potential
C Iadecola, MS Buckwalter… - The Journal of clinical …, 2020 - Am Soc Clin Investig
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function
AG Spiteri, CL Wishart, R Pamphlett, G Locatelli… - Acta …, 2022 - Springer
In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …
Diversity of macrophages in lung homeostasis and diseases
F Hou, K Xiao, L Tang, L Xie - Frontiers in immunology, 2021 - frontiersin.org
Lung macrophages play important roles in the maintenance of homeostasis, pathogen
clearance and immune regulation. The different types of pulmonary macrophages and their …
clearance and immune regulation. The different types of pulmonary macrophages and their …