Visual perception in humans occurs through absorption of electromagnetic radiation from
400 to 780 nm by photoreceptors in the retina. A photon of visible light carries a sufficient …

Over the last decade, huge progress has been made in the understanding of the molecular
mechanisms underlying inherited retinal dystrophy (IRD), as well as in the development and …

Rod and cone photoreceptors support vision across large light intensity ranges. Rods, active
under dim illumination, are thought to saturate at higher (photopic) irradiances. The extent of …

We introduce the software package ReaDDy for simulation of detailed spatiotemporal
mechanisms of dynamical processes in the cell, based on reaction-diffusion dynamics with …

The visual pigment rhodopsin belongs to the family of G protein-coupled receptors that can
form higher oligomers. It is controversial whether rhodopsin forms oligomers and whether …

Vertebrate photoreceptor cells are exquisite light detectors operating under very dim and
bright illumination. The photoexcitation and adaptation machinery in photoreceptor cells …

Although homo-and heterodimerizations of G protein-coupled receptors (GPCRs) are well
documented, GPCR monomers are able to assemble in different ways, thus causing …

G protein-coupled receptors (GPCRs) are central to many fundamental cellular signaling
pathways. They transduce signals from the outside to the inside of cells in physiological …

Calcium-signaling in cells requires a fine-tuned system of calcium-transport proteins
involving ion channels, exchangers, and ion-pumps but also calcium-sensor proteins and …

Any aspect of cell activity is regulated by extracellular signals that are recognized, decoded,
and transduced inside the cell via different classes of plasma membrane receptors. 1À3 G …