Heterotopic ossification (HO) is a diverse pathologic process, defined as the formation of
extraskeletal bone in muscle and soft tissues. HO can be conceptualized as a tissue repair …

Abstract This Consensus Statement covers recommendations for the diagnosis and
management of patients with pseudohypoparathyroidism (PHP) and related disorders …

Heterotopic ossification (HO) is the formation of extraskeletal bone in non-osseous tissues. It
is caused by an injury that stimulates abnormal tissue healing and regeneration, and …

The emerging field of regenerative medicine will require a reliable source of stem cells in
addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue represents an …

Adipose tissue is an abundant, accessible, and replenishable source of adult stem cells that
can be isolated from liposuction waste tissue by collagenase digestion and differential …

Tissue engineering offers considerable promise in the repair or replacement of diseased
and/or damaged tissues. The cellular component of this regenerative approach will play a …

Abstract The Hedgehog (Hh) signalling pathway plays many important roles in development,
homeostasis and tumorigenesis. The critical function of Hh signalling in bone formation has …

Acquired heterotopic ossification (HO) is a painful and debilitating disease characterized by
extraskeletal bone formation after injury. The exact pathogenesis of HO remains unknown …

FGF23 is a bone-derived hormone that regulates systemic phosphate homeostasis, vitamin
D metabolism and α-Klotho expression through a novel bone-kidney axis. FGF23 inhibits …

Context: The term pseudohypoparathyroidism (PHP) indicates a group of heterogeneous
disorders whose common feature is represented by impaired signaling of various hormones …