Autophagy refers to the formation of autophagosomes by membrane wrapping part of the
cytoplasm and the organelles and proteins that need to be degraded in the cells …

The mosaic theory of hypertension was advocated by Irvine Page~ 80 years ago and
suggested that hypertension resulted from the close interactions of different causes …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

During autophagy, phagophores grow into double-membrane vesicles called
autophagosomes, but the underlying mechanism remains unclear. Here, we show a critical …

The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for
cardiovascular diseases. It is now widely accepted that an experimental HSD can stimulate …

Dendritic cells (DCs) are chief inducers of adaptive immunity and regulate local
inflammatory responses across the body. Together with macrophages, the other main type of …

Abstract Background Ginsenoside Re is an active component in ginseng that confers
protection against myocardial ischemia/reperfusion (I/R) injury. Ferroptosis is a type of …

Background The adverse effect of excessive salt intake has been recognized in decades.
Researchers have mainly focused on the association between salt intake and hypertension …

Background: Dietary high salt (HS) is a leading risk factor for mortality and morbidity. Serum
sodium transiently increases postprandially but can also accumulate at sites of inflammation …

Tonicity-responsive enhancer-binding protein (TonEBP), which is also known as nuclear
factor of activated T cells 5 (NFAT5), was discovered 20 years ago as a transcriptional …