Acute lymphoblastic leukaemia
L Pagliaro, SJ Chen, D Herranz, C Mecucci… - Nature Reviews …, 2024 - nature.com
Acute lymphoblastic leukaemia (ALL) is a haematological malignancy characterized by the
uncontrolled proliferation of immature lymphoid cells. Over past decades, significant …
uncontrolled proliferation of immature lymphoid cells. Over past decades, significant …
Diagnosis, prognostic factors, and assessment of ALL in adults: 2024 ELN recommendations from a European expert panel
N Gökbuget, N Boissel, S Chiaretti, H Dombret… - Blood, 2024 - ashpublications.org
Working groups of the European LeukemiaNet have published several important consensus
guidelines. Acute lymphoblastic leukemia (ALL) has many different clinical and biological …
guidelines. Acute lymphoblastic leukemia (ALL) has many different clinical and biological …
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors
UBTF tandem duplications (UBTF-TDs) have recently emerged as a recurrent alteration in
pediatric and adult acute myeloid leukemia (AML). UBTF-TD leukemias are characterized by …
pediatric and adult acute myeloid leukemia (AML). UBTF-TD leukemias are characterized by …
[HTML][HTML] The gene expression classifier ALLCatchR identifies B-cell precursor ALL subtypes and underlying developmental trajectories across age
T Beder, BT Hansen, AM Hartmann, J Zimmermann… - …, 2023 - journals.lww.com
Abstract Current classifications (World Health Organization-HAEM5/ICC) define up to 26
molecular B-cell precursor acute lymphoblastic leukemia (BCP-ALL) disease subtypes by …
molecular B-cell precursor acute lymphoblastic leukemia (BCP-ALL) disease subtypes by …
Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL
Distinct diagnostic entities within BCR:: ABL1-positive acute lymphoblastic leukemia (ALL)
are currently defined by the International Consensus Classification of myeloid neoplasms …
are currently defined by the International Consensus Classification of myeloid neoplasms …
Transcription factor UBF depletion in mouse cells results in downregulation of both downstream and upstream elements of the rRNA transcription network
A Theophanous, A Christodoulou, C Mattheou… - Journal of Biological …, 2023 - ASBMB
Transcription/processing of the ribosomal RNA (rRNA) precursor, as part of ribosome
biosynthesis, is intensively studied and characterized in eukaryotic cells. Here, we …
biosynthesis, is intensively studied and characterized in eukaryotic cells. Here, we …
Insights into IGH clonal evolution in BCP-ALL: frequency, mechanisms, associations, and diagnostic implications
F Darzentas, M Szczepanowski, M Kotrová… - Frontiers in …, 2023 - frontiersin.org
Introduction The malignant transformation leading to a maturation arrest in B-cell precursor
acute lymphoblastic leukemia (BCP-ALL) occurs early in B-cell development, in a pro-B or …
acute lymphoblastic leukemia (BCP-ALL) occurs early in B-cell development, in a pro-B or …
Molecular subgroups of T-cell acute lymphoblastic leukemia in adults treated according to pediatric-based GMALL protocols
M Neumann, T Beder, L Bastian, S Hänzelmann… - Leukemia, 2024 - nature.com
In contrast to B-cell precursor acute lymphoblastic leukemia (ALL), molecular subgroups are
less well defined in T-lineage ALL. Comprehensive studies on molecular T-ALL subgroups …
less well defined in T-lineage ALL. Comprehensive studies on molecular T-ALL subgroups …
Diagnosis of acute lymphoblastic leukaemia: an overview of the current genomic classification, diagnostic approaches, and future directions
W Walter, I Iacobucci, M Meggendorfer - Histopathology, 2025 - Wiley Online Library
B‐acute lymphoblastic leukaemia (B‐ALL) is a haematological disease resulting from
haematopoietic system dysfunction, leading to the unchecked growth of immature B …
haematopoietic system dysfunction, leading to the unchecked growth of immature B …
Oncogenic lesions and molecular subtypes in adults with B‐cell acute lymphoblastic leukemia
T Yasuda, M Sanada, S Tsuzuki… - Cancer Science, 2023 - Wiley Online Library
B‐cell acute lymphoblastic leukemia (B‐ALL), a genetically heterogeneous disease, is
classified into different molecular subtypes that are defined by recurrent gene …
classified into different molecular subtypes that are defined by recurrent gene …